Protein Scientist, Biology

**Company**:
Chronic kidney diseases are a severe and growing worldwide health challenge that affects 1 in 7 people. Without effective treatments patients can experience kidney failure leading to dialysis and transplantation, a high burden to patients, families and the health care system. Despite recent advances for certain kidney disease patients, many forms of highly prevalent kidney diseases do not have effective treatments.

Borealis was founded on the premise that a convergence of scientific and translational breakthroughs will enable RNA therapeutics to address some of the largest untreated kidney diseases and beyond. Borealis builds on the success of Chinook Therapeutics, a kidney disease company with a research site in Vancouver that was acquired by Novartis in 2023 for up to $3.5 billion. The Borealis team has strong leadership and academic advisors who were central to research at Chinook, together with additional leadership in the field of RNA therapeutics. We are headquartered in Vancouver, BC, with state-of-the-art wet labs for molecular and cellular biology, in vivo pharmacology, chemistry, DMPK, bioinformatics and analytical capabilities.

**Position**:
**Responsibilities include**:

- Oversee antibody discovery campaign and support the design, generation, and screening of biologics of various formats
- Develop and perform biophysical and functional assays to profile lead compounds.
- Build internal capabilities for protein/drug-conjugate biophysical and functional characterization.
- Manage outsourcing for protein production and analysis with CROs.
- Actively communicate and present scientific findings in group discussions as well as inter-departmental and company-wide meetings.
- Collaborate and work with a diverse group of scientists across departments to ensure timely progress in research projects.

**Location**:

- This is an on-site lab-based position located in Borealis’ Vancouver, BC headquarters. Much of your time will be spent in conducting wet lab work.

**Education, Experience, and Skills**:

- PhD in Biochemistry, Biophysics, Molecular Biology or other relevant field with at least 1 year of directly related industry experience; MSc with minimum 5 years directly relevant industry experience, or other equivalent combination of education and experience.
- Expertise in protein/antibody design and engineering, with hands-on experience in biophysical and functional assays for characterization.
- Broad knowledge and/or experience in protein/antibody production, purification, and bioconjugation.
- Experience in CRO management or external collaboration.
- Good time management and communication skills.
- Fast learner, with great problem-solving skills to resolve potential issues that arise.
- Positive attitude and high personal and ethical standards.
- A strong team player with a passion for science and drug discovery.

**Compensation**:The annual salary range is $113,000 - $131,000 and Borealis Bio provides competitive benefits including RRSP matching, extended medical, dental, vision and a Wellness Spending Account up to $1,800 per year.
- Borealis is an Equal Opportunity Employer, and we prohibit discrimination or harassment of any kind. We are committed to fostering an environment where ALL people are welcome and supported. _We cultivate a culture of inclusion for all employees that respects their individual strengths, views, and experiences. We believe that our differences enable us to be a better team - one that makes better decisions, drives innovation, and delivers better business results. Creativity and innovation flourish in an environment of openness, inclusion, and mutual respect._