Analytical Scientist
2 weeks ago
Job Summary
We are seeking an Analytical Scientist to join our team at the National Research Council Canada. As an Analytical Scientist, you will play a key role in the characterization and development of biologics-based therapeutic drugs.
Key Responsibilities
- Support the development of analytical assays for biologics-based therapeutic drugs
- Characterize and develop biologics-based therapeutic drugs using various biochemical and biophysical techniques
- Collaborate with cross-functional teams to design, develop, and optimize analytical assays
- Contribute to the development of new biologics-based therapeutic drugs
- Perform basic searches for relevant information in technical manuals, online databases, and journal articles
Requirements
- Bachelor degree in Analytical Chemistry, Biochemistry, Biotechnology, Virology, Molecular Biology, Immunology or relevant related discipline
- Experience in supporting the development of analytical assays
- Experience in mammalian cell culture for use in cell-based assays
- Experience working with and characterizing viral vectors and other biologics-based therapeutics
- Experience in ELISAs and one or more of the following functional assays; surface plasmon resonance (SPR), biolayer interferometry(BLI), enzyme kinetics, flow cytometry, plate-based methods such as AlphaLisa, FRET, proximity ligation assay (PLA), fluorescence polarization (FP), time-resolved fluorescence (TRF)
- Some experience in one or more biophysical techniques such as analytical chromatography, analytical ultracentrifugation (AUC), capillary isoelectric focussing (cIEF), differential scanning calorimetry/fluorimetry (DSC/DSF), fluorescence-based spectroscopy, circular dichroism (CD), CE-SDS, western blots, PCR/qPCR/ddPCR/dPCR and dynamic light scattering (DLS), Western Blot
- Some experience molecular biology techniques or the use of design of experiments (DOE)
Working Conditions
- Reliability Status
- English or French
Assessment Criteria
- General knowledge of basic protein structure and biochemistry
- Working knowledge of the proper preparation, physical manipulation and storage of biological samples
- Working knowledge and understanding of basic biochemical, biophysical and functional assays for proteins
- Ability to contribute to the design, development and optimization of analytical assays
- Ability to clearly and accurately document results and analysis from experiments
- Ability to maximize efficient use of time by multitasking both inside and outside the laboratory
Benefits
- From $58,445 to $80,040 per annum
- NRC employees enjoy a wide-range of competitive benefits including comprehensive health and dental plans, vacation, sick, and other leave entitlements, disability insurance and pension plans
About the NRC
The National Research Council of Canada (NRC) is the Government of Canada's largest research organization supporting industrial innovation, the advancement of knowledge and technology development. We collaborate with over 70 colleges, universities and hospitals annually, work with 800 companies on their projects, and provide advice or funding to over 8000 Small and Medium-sized Enterprises (SMEs) each year.
We bring together the brightest minds to deliver tangible impacts on the lives of Canadians and people around the world. And now, we want to partner with you. Let your expertise and inspirations make an impact by joining the NRC.
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