Research Chemist

5 days ago

Vancouver, British Columbia, Canada Stein's Garden & Home Full time

Xenon Pharmaceuticals is advancing a product pipeline to address high unmet medical needs, including epilepsy and depression. Our flagship program represents the most advanced potassium channel modulator in clinical development for multiple indications.

We are seeking a Research Scientist 1/2, Chemistry to contribute to our drug discovery programs by applying synthetic and medicinal chemistry skills. This individual will design and implement basic medicinal chemistry targets and execute synthesis, purification, and characterization.

Key Responsibilities:

  • Design drug candidates that advance SAR based on biological, DMPK, and physicochemical properties data.
  • Analyze data, interpret results, and recommend action.
  • Utilize computational chemistry tools for hypothesis-driven medicinal chemistry.
  • Demonstrate leadership in staying up-to-date with scientific developments, patents, and medicinal chemistry literature.
  • Prepare technical reports, SOPs, patent procedures, summaries, and quantitative analyses.
  • Communicate research results at internal and external meetings.
  • Work closely with project teams to generate and implement medchem strategies and coordination with intellectual property and other functions.
  • Maintain a detailed laboratory notebook and ensure it's accurate.
  • Ensure the laboratory environment is safe and well-organized.

Requirements:

  • MSc degree with 4+ years of experience or PhD degree with 2+ years of experience in chemistry.
  • Able to draw on literature and utilize computational chemistry tools to generate hypothesis-driven medicinal chemistry targets.
  • Experience working in a cross-functional environment in a flexible manner.

The estimated salary range for this role is $86,000 - $114,000 CAD. Our Total Rewards program includes base salary, target bonus, stock options, medical, dental, vision, short- & long-term disability, accidental death & dismemberment, life insurance, Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions.

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