Genomic Bioinformatician

Hamilton Health Sciences is seeking a highly skilled Genomic Bioinformatician to join our team. As a key member of our laboratory, you will be responsible for managing, analyzing, and integrating large-scale gene sequence data.

• Develop and implement pipelines to align, normalize, visualize, and analyze data
• Integrate data and results with internal and external applications and databases
• Collaborate with members of the Hamilton Regional Genetics Program and other key partners
• Stay up-to-date with new and emerging technologies and literature in high-throughput genomic analysis
• Conduct literature reviews and develop pipelines for processing next-generation sequencing data
• Establish and maintain a secure and effective server system for data processing
• Liaise with laboratory scientists to submit variant classification data to appropriate databases
• Troubleshoot and resolve issues related to software used for detecting and interpreting sequence and copy number variants

• Master's Degree or Ph.D. in bioinformatics, computer science, or molecular biology and genetics
• Experience with programming languages such as Python, R, C++, and Java
• Experience working with next-generation sequencing data and developing NGS bioinformatics pipelines
• Experience with full-stack development, databases, frameworks, and APIs
• Experience with relevant public databases and data cleaning, normalization, and visualization methods

• Experience working with SNP-microarray analysis and epigenomic data analysis
• Familiarity with statistical genomics and ACMG/AMP/ASCO/CAP guidelines for variant annotation and classification

Hamilton Health Sciences fosters a culture of patient and staff safety, and all employees are guided by our Mission, Vision, Values, and Values-Based Code of Conduct. We are an equal opportunity employer and will accommodate any needs under the Canadian Charter of Rights and Freedom, Accessibility for Ontarians with Disabilities Act, and the Ontario Human Rights Code.