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Chemist, Research and Development

2 months ago


Richmond Hill, Ontario, Canada Apotex Full time

About Apotex Inc.

Apotex Inc. is a leading global pharmaceutical company that specializes in the development, manufacturing, and distribution of high-quality, affordable medicines for patients worldwide. With a strong presence in over 75 countries, Apotex employs a diverse team of professionals in various fields, including research and development, manufacturing, and commercial operations.

Job Summary

  • Responsible for conducting analytical testing of raw materials, in-process materials, finished products, and stability samples to ensure compliance with regulatory requirements and company standards.
  • Collaborate with the analytical development department to develop and validate analytical test methods, ensuring accuracy and precision.
  • Prepare and submit stability summary reports to regulatory authorities and internal stakeholders.
  • Develop and maintain stability schedules for various drug products, ensuring timely and accurate reporting.

Key Responsibilities

  • Under minimal supervision, perform analytical testing using various instruments and established procedures, ensuring high accuracy and precision.
  • Document test results clearly and accurately, adhering to standard operating procedures (SOPs) and regulatory requirements.
  • Provide statistical analysis of test results as required, ensuring timely and accurate reporting.
  • Organize work efficiently, utilizing time effectively to meet deadlines and ensure compliance with regulatory requirements.
  • Communicate technical information clearly and concisely, both verbally and in written form, to internal stakeholders and regulatory authorities.
  • Perform intermediate precision testing as part of method transfer, under supervision, to ensure accuracy and precision.
  • Other responsibilities as assigned by the supervisor, including participating in training and development programs to enhance technical knowledge and skills.

Technical Requirements

  • Sound working knowledge of UV-VIS spectrophotometer, Karl Fisher, Auto-titrator, HPLC, GC, IC, balances, vacuum oven, microscope, osmometer, density meter, Hunter scan, and Auto-actuation station.
  • Ability to operate complex analytical instruments and techniques as required.

Relationship with Internal/External Customers & Stakeholders

  • Act as a key player within the team, providing technical expertise and support to senior chemists and other stakeholders.
  • Liaise regularly with internal customers to understand their needs and provide timely updates on work progress.

Problem Solving Analysis

  • Solve routine problems independently, utilizing technical knowledge and skills to resolve issues.
  • Identify complex problems with instruments, specifications, and test methods, and report them to senior-level personnel for corrective action.

Decision Making/Autonomy

  • Respond to queries from junior chemists and participate in training new staff as required, demonstrating technical expertise and leadership skills.

Leadership/Professional Development of Self & Others

  • Continuously upgrade technical knowledge by attending seminars, workshops, and training programs, staying up-to-date with industry developments and best practices.

Compliance & Due Diligence

  • Perform all activities in compliance with SOPs, cGMP, and SHE policies, ensuring adherence to regulatory requirements and company standards.
  • Participate in reviewing department policies, procedures, and standards impacting their area, as required.

Job Requirements

  • Bachelor of Science in chemistry or related field.
  • Minimum 3 years of experience in pharmaceutical analytical laboratory.
  • Operational and good trouble-shooting skills related to analytical instruments.
  • Good knowledge of GMP, GLP, and WHMIS.
  • Good knowledge of Pharmaceutical compendia.