Senior Computational Biologist

2 months ago

Vancouver, British Columbia, Canada AbCellera Full time $75,200 - $94,000
About the Role

We are seeking a highly motivated and experienced Senior Computational Biologist to join our team at AbCellera. As a key member of our research team, you will be responsible for implementing in-silico structural tools and processes in the areas of protein and antibody engineering.

Key Responsibilities
  1. Design, implement, and evaluate in-silico protein engineering activities in support of a developing platform for antibody reformatting processes and optimization of therapeutic assets.
  2. Collaborate with teams across the company to understand engineering challenges and propose solutions.
  3. Prepare and author materials to educate colleagues, and communicate strategies, key findings, and implications.
  4. Organize, support, and collaborate with other team members to meet project deliverables and timelines.
Requirements
  1. You have a PhD in Biochemistry, Biophysics, Structural Biology, Computational Biology, Computer Science, or a related field, or a MSc with 5+ years of related experience in a biological research setting.
  2. You have excellent programming skills in Python, as well as a comprehensive understanding of techniques to perform in-silico protein structure design using tools such as Rosetta software suite.
  3. You have working knowledge of antibody structure and function, and familiarity with techniques applicable to the molecular design, engineering, and experimental evaluation of antibody and/or antigen libraries for protein engineering purposes.
  4. You have awareness of experimental analytic and biophysics techniques used for antibody characterization, e.g. size exclusion chromatography (SEC), hydrophobic interaction chromatography (HIC), capillary electrophoresis (CE), light scattering (DLS, MALS), differential scanning calorimetry (DSC), isoelectric focusing (IEF), surface plasmon resonance (SPR), etc.
What We Offer

AbCellera offers a competitive salary range of CAD $75,200 - $94,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution. You will also have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, opportunity for flexible work arrangements, professional development opportunities, and comprehensive health benefits.

About AbCellera

AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.

We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success.

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