Bioinformatics Manager

1 day ago


Toronto, Ontario, Canada OICR Full time
About OICR

OICR is a leading cancer research institute in Ontario, Canada. Our mission is to deliver real-world solutions to find cancer earlier and treat it more effectively.

Job Summary

We are seeking a highly skilled Bioinformatics Manager to oversee a team of bioinformaticians, research/scientific associates, and software developers in the development and reporting of clinical genomics reports.

Key Responsibilities
  • Oversee the development and reporting of clinical genomics reports
  • Develop and support the open-source laboratory information management system MISO LIMS and associated applications
  • Automate and streamline data analysis, tracking, and workflow management using workflow systems like Cromwell
  • Archive data for long-term storage and release data to collaborators and public archives
  • Perform project-specific analysis for collaborators, including alignment, de novo assembly, variant detection, quantification of tumour heterogeneity and purity, RNAseq analysis, variant significance prediction, and structural variant calling
  • Analyze and interpret genomic data using accredited pipelines and processes and draft reports for clinical cases
  • Manage and coordinate a team of cancer genome interpreters to generate clinical genome reports incorporating genome, transcriptome, cell-free, and other emerging genomic data types
Requirements
  • Completion of a Master's degree in a scientific discipline, preferably in bioinformatics, oncology, genetics, molecular biology, or recognized equivalent
  • Deep hands-on technical expertise and excellent analytical abilities
  • Acute attention to detail and rigor required for developing clinical testing applications
About OICR

OICR is committed to fostering a climate of equity, diversity, inclusion, and accessibility. We welcome and respect the diversity of all members of our community and we support an inclusive culture for all.



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