Bioinformatics Expert

1 week ago


Mississauga, Ontario, Canada F. Hoffmann-La Roche Gruppe Full time
About the Role

We are seeking a highly motivated Senior Bioinformatics Scientist to join our Reagent Bioinformatics team in Roche Diagnostics Solutions. The successful candidate will collaborate with data scientists, bioinformaticians, protein engineers, and molecular biologists to create and continuously improve proteins and enzymes critical to our portfolio of reagents, assays, and instruments.

Key Responsibilities
  1. Develop machine learning models to design and optimize proteins to achieve R&D project goals in cross-functional teams.
  2. Benchmark the performance of deep learning models (e.g., language models, graph neural networks, diffusion models) across varied projects and datasets.
  3. Streamline data preparation and the deployment, training and/or fine-tuning of ML models.
  4. Keep abreast of the latest developments in machine learning and integrate these methods into existing workflows, when appropriate.
  5. Present and communicate project updates to diverse teams in the organization.
Requirements
  1. You bring a minimum of 3 or more years of experience with a Ph.D. or equivalent experience in fields such as Computer Science, Machine Learning, Statistics, Biophysics, Computational Biology, Structural Biology, or related disciplines.
  2. Excellent programming skills in Python, proficiency with machine learning libraries like PyTorch and TensorFlow, and experience with version control systems such as Git.
  3. Demonstrated experience applying and training deep learning models to solve biological problems, with an emphasis on machine learning-based protein engineering.
  4. Experience in high-performance computing environments, particularly with distributed model training, and developing shared codebases.
  5. Strong written and verbal communication skills, with the ability to collaborate effectively across multidisciplinary teams and adapt communication for varied technical audiences.
About Us

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche Pharma Canada has its office in Mississauga, Ontario and employs over 850 employees. The Mississauga facility is bright, vibrant, fosters collaboration and teamwork, and is reflective of Roche's truly innovative culture.



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