Bioanalytical Assay Director

1 month ago


Vancouver, British Columbia, Canada Abdera Therapeutics Full time
About Abdera Therapeutics

Abdera Therapeutics is a pioneering precision oncology company dedicated to developing innovative targeted radiation therapies. Our cutting-edge modular technology platform enables the rapid development of safe and efficacious therapies for cancer patients with limited treatment options.

We are seeking a highly skilled and experienced Bioanalytical Assay Director to join our growing team. As a key member of our research organization, you will play a critical role in advancing our bioanalytical capabilities and contributing to the development of novel cancer therapies.

Key Responsibilities
  1. Develop and implement bioanalytical strategies to evaluate PK, PD, metabolites, biomarkers, and immunogenicity to support preclinical and clinical development.
  2. Provide scientific and technical oversight to facilitate bioanalytical assay design, method development, optimization, validation, and sample analysis in-house and at contract research organizations (CROs).
  3. Identify new assays and technologies to expand preclinical and clinical analytical capabilities that contribute to developing targeted cancer radiotherapies.
  4. Lead, develop, and train members of the bioanalytical team and plan for resourcing needs.
  5. Evaluate and review data, protocols, and reports and ensure completion and maintenance of documentation, including electronic lab notebook (ELN) entries.
  6. Contribute to authoring regulatory filings and manuscripts.
  7. Collaborate with cross-functional team members to provide bioanalytical expertise, present data, and advance programs.
Requirements
  • PhD in Cell and/or Molecular Biology, Biochemistry, Immunology, Pharmacology, or related disciplines with 12+ years of relevant experience, or an equivalent combination of graduate education and industry experience.
Skills and Abilities
  • Track record and expertise with developing bioanalytical assay methods.
  • Demonstrated advanced knowledge and technical hands-on experience in bioanalytical and biomarker assays, cell-based assays, ELISA/MSD, ADA, immunohistochemistry, and flow cytometry.
  • Direct experience leading teams, managing CROs, and developing and maintaining effective working relationships with key partners.
  • Competency with analysis methods and relevant software, including Prism, Excel, statistical analysis, and Benchling (or other ELN).
  • Prior experience preparing documentation for regulatory filings and knowledge of regulatory requirements for bioanalytical assays.
  • Proven ability to work collaboratively in a cross-functional team.
  • Proven ability to manage concurrent deliverables in a fast-paced, milestone-driven environment.
  • Excellent communication and presentation skills.
  • Excellent attention to detail and accuracy.
Abdera Therapeutics is an Equal Opportunity Employer

We are committed to diversity and inclusion in the workplace and prohibit harassment of any kind and any form of discrimination based on protected characteristics.

Please include a cover letter and current resume to apply.



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