Director/vice President, Translational Research
2 weeks ago
**35Pharma **is a clinical-stage biopharmaceutical company that designs and develops innovative therapeutics for life threatening lung diseases, and musculoskeletal and metabolic disorders. We believe in connecting rigorous science with our innate sense of urgency to rapidly generate breakthrough therapies for patients in need to better quality of life. Our highly qualified team of drug developers and company builders has a track record of advancing complex biologics from discovery through clinical trials. Our R&D facilities are located in the heart of **Montréal, Canada**, and comprise laboratory space for pre-clinical research as well as manufacturing development that bolster our mission to serve patients in need.
We are currently looking for a full-time proactive, positive and self-motivated **Director/Vice President, Translational Research** who will join our growing team to develop medicines that radically transform patients’ lives.
This position will be integral to the translation of our discovery programs into clinical development. Under the direction of the Chief Scientific Officer and in collaboration with the Clinical and Discovery teams, the **Director/Vice President, Translational Research** will lead our mode of action studies across pre-clinical experiments and early clinical trials with a shared commitment to high quality and performance.
The position would be an excellent fit for a professional with demonstrated experience developing and executing biomarker discovery strategies, assessing PK/PD relationships and supporting the translation of early-stage drug discovery programs into the clinic.
**You will love this job if**:
- You have a passion for science and drug development
- You thrive in a fast-paced environment with lots of responsibility and opportunity to learn
- You enjoy working as a team player and value good communication
**Key Responsibilities**:
- Provides scientific leadership in areas of biomarker discovery, development and translational science working with multiple cross-functional teams
- People management: Coach, develop and supervise a team of highly motivated translational scientists and research associates
- Collaborate with Preclinical Development, Clinical Operations teams, and external experts as appropriate to develop scientifically rigorous translational and exploratory biomarker strategies that assess mode of action and PK/PD relationships across pre-clinical studies and clinical trials
- Support scientific input and review of all translational medicine aspects of clinical and regulatory documents, including but not limited to development plans, study protocols, laboratory manuals, clinical study reports, regulatory submissions, and responses to any regulatory questions, etc.
- Propose and develop innovative methods and technologies as well as new directions for project development
- Function as a scientific and business thought-leader inside and outside of the company and a key link to external scientific and medical community
- Provide oversight of external vendors who are delegated responsibilities
- PhD (and/or MD) with primary focus in either Cellular or Molecular Biology, Medicine, Pharmacology or a related field with at least 10 years of pharmaceutical or biotechnology industry experience in pre-clinical / early clinical or translational science
- Thorough understanding of clinical trials and clinical strategy, experience with drug development as well as the assessment of PD markers in a clinical setting
- Proven ability to drive and influence projects from discovery through early clinical development with a focus on providing clinical proof of biology
- Expertise assessing and developing PK/PD relationships
- Expertise in establishing and running preclinical studies
- Familiarity with data management and visualization tools and collaborating with computational biology experts to analyze complex genomic and proteomic data sets
- Experienced line and matrix manager
- Flexible, independent and self-motivated, able to handle multiple tasks and priorities
- Strong verbal and written communication skills
**Perks**:
- Comprehensive group insurance plan
- Paid public transit
- Beautiful office space in Montreal’s Old Port
- Onsite yoga and healthy snacks
- A team and culture committed to learning and high performance
**Next steps**:
- we are looking forward to hearing from you
**Job Types**: Full-time, Permanent
**Benefits**:
- Commuter benefits
- Company events
- Dental care
- Disability insurance
- Employee assistance program
- Extended health care
- Flexible schedule
- Life insurance
- Paid time off
- Vision care
- Wellness program
Schedule:
- Monday to Friday
**Education**:
- Doctoral Degree (preferred)
**Experience**:
- biomarker discovery and companion diagnostics: 10 years (required)
Work Location: In person
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