Scientist, Chemistry

3 weeks ago

SaintLaurent, Canada NuChem Full time

We are a dynamic team consisting of experienced scientists and fresh graduates where everyone contributes their ideas and talents towards a variety of diverse projects. We believe in a work environment that should be fun, safe and productive with fully equipped, state-of-the art laboratories and flexible work hours. We are focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

We are seeking a highly motivated entry-level synthetic organic or medicinal chemist to join our established team working on a variety of programs including hit-to-lead development, lead optimization, route scouting and compound scale-up. The highly qualified individual is expected to have experience in modern organic synthesis with good laboratory skills and high productivity. Key aspects of the role are being able to work within a team structure, propose and execute synthetic routes and engage in troubleshooting exercises when needed.

**RESPONSIBILITIES**:

- Utilize cutting-edge synthetic methodologies and techniques to design and execute efficient syntheses of target compounds for existing chemical series and novel series;
- Independently conduct multi-step synthesis and optimization through effective reaction planning, troubleshooting, and systematic analysis;
- Purify and characterize compounds using a variety of techniques including column chromatography, crystallization, trituration, LCMS, NMR, HPLC;
- Work under the supervision of the Director of Chemistry or the Project Manager in order to achieve the objectives of the project in line with those of the client;
- Research current literature to formulate synthetic and medicinal chemistry strategies. Evaluate and implement new reactions, techniques and technologies to advance the projects;
- Maintain lab notebook, instrument and inventory records in accord with department guidance;
- Maintain all appropriate standards for lab safety and hazardous material management.

**REQUIREMENTS**:

- PhD in Organic Chemistry or Medicinal Chemistry;
- Strong knowledge and experience in current synthetic methods;
- Expertise in isolation and purification techniques such as silica gel chromatography and HPLC as well as modern analytical techniques such as NMR and LCMS;
- Knowledge of good laboratory and safety practices.
- Excellent written, organizational and documentation skills;
- Proactive with strong interpersonal skills; able to thrive in a team-based environment;
- Demonstrated ability to troubleshoot and creatively problem solve;
- Proficiency in Microsoft Office (Word, Excel and PowerPoint);
- Ability to communicate progress effectively with colleagues and managers;
- New employees will be required to provide proof of a complete COVID-19 vaccination;
- Applicants must be eligible to work in Canada (Canadian citizen, permanent resident or work permit).

**COMPENSATION AND BENEFITS**:
**Salary**:

- Competitive and based on experience.

**Additional pay**:

- Annual bonus incentive plan.

**Advantages**:

- Full time permanent position;
- Health and dental care insurance plan;
- Short
- and long-term disability insurance;
- Life insurance;
- RRSP employer’s matching program;
- Casual dress code;
- Flexible schedule;
- On-site free parking;
- Continuing education;
- Career development.

**Schedule**:

- Monday to Friday.

French version

Nous sommes une équipe dynamique composée de scientifiques expérimentés et de jeunes diplômés où chaque scientifique contribue activement par leurs idées et leurs talents à divers projets de découverte de médicament. Nous croyons à un environnement de travail agréable, sécuritaire et stimulant dans nos laboratoires à la fine pointe de la technologie. Nous nous efforçons d’attirer, de fidéliser, de développer et de faire progresser nos employés à leur plein potentiel en récompensant les façons de penser audacieuses et en intégrant des comportements inclusifs dans chaque aspect de notre travail.

RESPONSABILITÉS:

- Utiliser des méthodologies et de nouvelles techniques de synthèse pour concevoir et exécuter des synthèses efficaces de composés cibles pour des séries chimiques existantes et de nouvelles séries;
- Effectuer indépendamment l’optimisation des synthèses en plusieurs étapes grâce à une planification efficace des réactions, par la résolution de problème et par une analyse systématique;
- Purifier et caractériser les composés en utilisant une variété de techniques, y compris la chromatographie sur colonne, la cristallisation, la trituration, LCMS, RMN, HPLC;
- Travailler sous la supervision du Directeur de la chimie ou du Gestionnaire de projets afin d’atteindre les objectifs du projet en ligne avec ceux du client;
- Communiquer de façon efficiente les résultats;
- Tenir à jour le cahier de laboratoire, les instruments et les registres d’inventaire co

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