Post Doctorate Fellow

3 weeks ago

Hamilton, Canada McMaster University Full time

The David Braley Research Institute (affiliated with McMaster University) has an immediate opening for a full-time, experienced **Postdoctoral Fellow in Immuno-Metabolism **in the laboratory of Dr. Marc Jeschke - Professor of Surgery, Vice President of Research at Hamilton Health Sciences.

Our laboratory focuses on translational research to attenuate trauma-induced stress, hypermetabolism, inflammation and sepsis.

Our laboratory has recently shown that the adipose tissue and its ensuing browning plays a major role in hypermetabolism which is associated with substantial adverse clinical outcomes for years. The goals of our research are to develop novel treatments and interventions to attenuate the browning response and to potentially implement novel clinical treatments.

**About the Department of Surgery**

Over its 50+ year history, the McMaster Department of Surgery has maintained a steadfast commitment towards thinking big and making it possible. We are a Department with 11 surgical divisions and Royal College residency training programs; together, we are poised to unleash a future fueled by a creative mindset and powered by our people.

**C.R.E.A.T.E.**
Tenet 1: Building A Culture that Inspires
Tenet 2: Conduct Research that Impacts
Tenet 3: Educate, to Honour our Students
Tenet 4: Advance, Personally, Professionally and Globally
Tenet 5: Transform Patient Care
Tenet 6: Unleash surgical Enterprise as a mindset.

**Description**:
**Skills and Qualifications**:

- PhD (or combined MD/PhD) in Cell Biology or Metabolism, with strong background in lipids and adipose tissue research
- Experience in some or all of the following techniques: flow cytometry with multi-color panel design for immune cell profiling & immune cell sorting, assessments of immune cell function and immunometabolism both in vitro and in vivo, biochemical techniques (e.g. western blot, IP’s, etc.), primary cell culture, animal/rodent models, molecular biology techniques (real-time gene expression, etc.), tissue processing, imaging (e.g. confocal microscopy)
- Study design and hands-on execution & interpretation of mitochondrial respiration measurement and mito stress tests
- Experience in study design and result interpretation involving metabolomics, proteomics, and scRNA-seq considered as strong assets
- Self-motivated, detail-oriented, and results-driven
- Strong ability to take initiative and work independently, as well as in a team environment
- Excellent written and oral communication skills
- Proven track record of publications in high quality journals required (minimum of 5 publications); some successful minor grant funding desirable

**Duration and Funding**:
**How To Apply**

The David Braley Research Institute is committed to providing accessible employment practices that are in compliance with the Accessibility for Ontarians with Disabilities Act (‘AODA’). If you require accommodation for disability during any stage of the recruitment process, please indicate this in your cover letter.

**Employment Equity Statement**

McMaster University is located on the traditional territories of the Haudenosaunee and Mississauga Nations and within the lands protected by the “Dish With One Spoon” wampum agreement.

The diversity of our workforce is at the core of our innovation and creativity and strengthens our research and teaching excellence. In keeping with its Statement on Building an Inclusive Community with a Shared Purpose, McMaster University strives to embody the values of respect, collaboration and diversity, and has a strong commitment to employment equity.

Job applicants requiring accommodation to participate in the hiring process should contact:

- Human Resources Service Centre at 905-525-9140 ext. 222-HR (22247), or
- Faculty of Health Sciences HR Office at ext. 22207, or
- School of Graduate Studies at ext. 23679

to communicate accommodation needs.

**Vaccination Mandate - FHS**

This position is located in a host hospital or other healthcare site that has an active vaccination mandate in place. Successful applicants will need to comply with these and any other health and safety measures necessary as part of their appointment.

**Hybrid Work Language**

To ensure an ongoing and vibrant University community that meets the needs of our students, staff and faculty and supports the University mission, ability to work on-site continues to be a requirement for most University positions. The University is supportive of exploring flexible work arrangements that effectively balance operational needs and employee interests.

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