Downstream Process Development Intern

2 months ago


Vancouver, Canada AbCellera Biologics Full time

AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and T-cell engagers for cancer, and complex transmembrane proteins for indications such as metabolic and endocrine conditions, pain, and autoimmunity.

We are looking for a motivated and talented individual currently pursuing a Bachelor’s of Science degree in a relevant field to join our Downstream Process Development team as a co-op or intern for an 8 month term, starting in May 2025. This role would be contributing to the optimization of our purification process for monoclonal antibodies (mAbs) by primarily focusing on the clearance of problematic impurities and studying their behavior and removal with different purification techniques to aid in selection of optimal process conditions.

While in this on-site position, based in beautiful Vancouver, you will receive guidance and support from experienced team members within the Downstream Process Development team. The internship is designed to offer exposure to real-world projects and the opportunity to contribute to the advancement of antibody-based medicines from target to clinic within Canada.

**How you might spend your days**
- Gaining hands-on experience in molecular biology, protein expression, purification, and characterization techniques
- Developing skills in chromatographic (AKTA) and analytical methods (UPLC, ELISA) used in biopharmaceutical downstream processing
- Gaining insights into the challenges and strategies associated with impurity clearance in mAb production
- Enhancing your critical thinking, problem-solving, and data analysis skills
- Developing your scientific communication, teamwork, and presentation skills

**We'd love to hear from you if**
- You have an understanding of or interest in downstream purification principles, including chromatography, normal flow filtration, tangential flow filtration, and centrifugation
- You are enrolled in a Bachelor's of Science degree in Biotechnology, Biochemical Engineering, Biomedical Science, or a related field
- You have acquired foundational laboratory skills such as pipetting, solution preparation, pH titration, centrifugation
- You have exposure to or experience in molecular biology and/or chromatography techniques
- You have experience in data analysis and statistical tools/software
- You have strong problem-solving and troubleshooting skills
- You have excellent written and verbal communication skills
- You have the ability to work collaboratively in a multidisciplinary team environment
- You are highly attentive to detail and have the ability to maintain accurate experimental records

**What we offer**

AbCellera’s hiring range for this role is CAD $3,300 - $3,700 per month, commensurate with your education and job-related knowledge, skills, and experience. In addition to base pay, we offer a number of ways to support AbCellerites in maximizing their work-life synergy. You will have a vacation allowance as well as additional days off as part of our company-wide office closures (a real value to all), and sick leave time while on your internship. Scientific and technical mentorship is a priority. And you’ll find we prioritize teams and social groups to build community and connections across AbCellera.

**About AbCellera**

AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.

And it all starts with our team. We’ve built a place where people feel they are part of something bigger than themselves. A place that exists to push the limits of science and technology, and aims to bring better therapies to patients.

We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success.

**To apply**

**Application deadline**:December 6, 2024

**Start date**:May 1, 2025

**Duration**: 8 months

**Location**:Vancouver, BC

**Workplace arrangement**:On-site

LI-DNP



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