Staff Software Engineer

Staff Software Engineer (Solution Architect) What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life‑changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world‑changing projects, you will do more and become more than you ever thought possible. Internal Title: Staff Software Engineer Position Summary: We are seeking an experienced Staff Software Engineer to lead the design and implementation of scalable, secure, and business‑aligned solutions within our cloud ecosystem. This role serves as the link between business strategy and technology execution, demanding strong technical expertise across diverse technologies. You will collaborate closely with stakeholders to translate business requirements into effective architectural designs. As a key technical leader, you will mentor engineering teams, define system architecture, and ensure our technology roadmap supports sustainable business growth and success. Responsibilities Lead the design and architecture of cloud‑native solutions that align with business objectives and user needs. Partner with business units, product managers, UX teams, and engineering to define end‑to‑end solutions that balance functionality, scalability, performance, and cost‑effectiveness. Act as the architectural owner across application layers—UI, backend services, APIs, databases, and cloud infrastructure, performing code review. Guide the integration of AI/ML, data engineering, and operational workflows into cohesive business solutions. Use BI tools such as Power BI and/or Tableau. Produce clear architectural documentation, solution proposals, and system blueprints to drive implementation. Uphold enterprise standards for security, performance, and maintainability. Provide leadership during system troubleshooting and contribute to incident resolution with a holistic architectural perspective. Support strategic planning, technical roadmaps, and continuous improvement initiatives in line with business growth. Train and mentor junior team members and peers. Requirements Bachelor’s or Master’s Degree in Computer Science, Engineering, or a related discipline. Minimum 8+ years in project lifecycle, with at least 3 years focused on architecture or technical design. Strong technical foundation in Node.js / Express / NestJS (JavaScript / TypeScript), Angular, and modern full‑stack development. Knowledge of .NET (C#) is an added advantage. Experience with CI/CD and DevOps tools such as GitHub Actions, TeamCity, or Jenkins. Experience on cloud platforms (AWS/Azure) and container orchestration (Docker, Kubernetes). Knowledge of performance monitoring tools like Splunk or Grafana. Experience optimizing system performance, diagnosing and addressing bottlenecks, and troubleshooting complex systems. Familiarity with data architecture, quality, and governance best practices. Strong business alignment and stakeholder communication skills—ability to translate business needs into technical solutions and communicate effectively. Leadership and mentorship capabilities—guiding teams, promoting best practices, and driving continuous improvement. Relevant certifications (e.g., Azure Solutions Architect Expert, AWS Solutions Architect) are a plus. Ability to apply advanced, wide‑ranging experience and professional knowledge to provide creative and effective solutions. Strong understanding of principles and policies to support new ideas and inter‑disciplinary collaboration. Ability to solve complex problems requiring in‑depth evaluation of factors and procedures. All listed requirements are deemed essential functions for this position; however, business conditions may require reasonable accommodation for additional tasks and responsibilities. We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We proudly maintain a zero‑net gap in pay, regardless of gender, ethnicity, or race. Several Employee Resource Groups (ERG) deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. Illumina is an equal‑opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partnership status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact **************@illumina.com. To learn more, visit: The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. Be careful – don’t provide your bank or credit card details when applying for jobs. Don’t transfer any money or complete suspicious online surveys. If you see something suspicious, report this job ad. #J-18808-Ljbffr