Research Associate

7 days ago

Vancouver, Canada University of British Columbia Full time

Academic

Job Category

Faculty Non Bargaining

Job Title

Research Associate

Department

Research | Leslie | Michael Smith Laboratories | Faculty of Science (Sabrina Leslie)

Posting End Date

August 10, 2025

Note: Applications will be accepted until 11:59 PM on the Posting End Date.

Job End Date

Aug 31, 2026

The expected pay range for this position is $72,000-$80,000 per year.

Research Associate in Single-Molecule Biophysics

) is pioneering single-molecule and single-nanoparticle imaging techniques using custom optical microscopy setups, resulting in new insights for drug developers to better design and optimize nanomedicines.

About the position: The Research Associate will lead experimental efforts to quantitatively characterize LNP structure, composition, and RNA delivery performance at the single-particle level. Leveraging advanced imaging workflows, including single-molecule fluorescence microscopy and high-throughput particle assays, the Research Associate will generate high-dimensional datasets necessary to further optimize LNP formulations.

Key responsibilities:

- Operate and optimize advanced fluorescence microscopy platforms (e.g., single-molecule fluorescence, confocal, super-resolution).
- Design custom image analysis workflows to extract particle-level metrics such as size, shape, RNA encapsulation, and delivery efficiency.
- Work collaboratively with chemists, biophysicists, and LNP formulation scientists at UBC and with external partners.
- Mentor and supervise trainees (graduate students, undergraduate researchers).
- Disseminate findings through lab meetings, conference presentations, and peer-reviewed publications.
- Assist in writing research grant proposals and progress reports.
- Ph.D. in Physics, Biophysics, Biomedical Engineering, Nanomedicine, or a closely related field.
- Minimum of 2-3 years of postdoctoral experience in advanced fluorescence microscopy, single-molecule imaging, or nanoparticle characterization.
- Demonstrated expertise in quantitative fluorescence imaging and single-particle analysis.
- Proficiency in computational tools for image analysis (e.g., MATLAB, Python) and statistical data analysis.
- Strong background in lipid nanoparticle systems and RNA delivery technologies is highly desirable.
- Experience in developing novel imaging assays and analyzing multi-parametric datasets.
- Proven record of scholarly productivity, including peer-reviewed publications.
- Excellent interpersonal, mentorship, and communication skills.
- Ability to work independently and collaboratively within a dynamic and multidisciplinary research environment.

The Research Associate will play a key role in developing next-generation imaging technologies for nanoparticle characterization, gaining valuable experience in advanced single-molecule techniques and RNA therapeutics research. This role offers excellent opportunities for scientific leadership, publishing high-impact papers, and contributing to interdisciplinary collaborations with academic and industry partners, setting a strong foundation for future career advancement in academia, biotechnology, or pharmaceutical sectors.

The expected pay range for this position is $72,000-$80,000 per year.

Application Process: We encourage interested applicants to submit a CV and cover letter that details their experience and contact details for 3 references to the UBC Careers portal. Application materials should be submitted no later than the posting end date.

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