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Lead Manufacturing Bioprocess Technician
2 weeks ago
AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and T-cell engagers for cancer, and complex transmembrane proteins for indications such as metabolic and endocrine conditions, pain, and autoimmunity. We are looking for an enthusiastic Lead Manufacturing Bioprocess Technician to become a key member of the clinical manufacturing team. You will play a crucial role in building critical manufacturing processes for the production of antibody-based medicines and training an exceptional team of Manufacturing Bioprocess Technicians. **How you might spend your days** - Working cross functionally with multiple teams including MSAT, Process Development, QA/QC, and Engineering to support the build required elements of an advanced bioprocessing facility to deliver the next generation of therapeutic antibodies - Leading and mentoring team members for manufacturing operations - Designing and operating manufacturing systems and processes that are effective, efficient, and technically sound, and that comply with cGMP requirements - Ensuring the facility, equipment, materials, and documents are established and maintained to support the capacity/throughput for the manufacturing process - Supporting manufacturing processes such as, but not limited to, cell line initiation (vial thaw), cell line scale-up, bioreactor operations, harvest clarification, TFF, column packing, chromatography, bulk drug substance fill, media and buffer preparation, weigh and dispense operations and drug product filling - Helping lead equipment FAT, SAT, and facility start-up as needed - Helping author and revise cGMP documentation (batch records, protocols, SOPs) and performing periodic review of cGMP documentation to ensure accuracy as well as supporting investigations related to the manufacturing process. - Contributing and assisting with internal audits as well as facility audits from the FDA, Health Canada and other regulatory bodies **We'd love to hear from you if** - You have an AS/BSc/BA in Biological Sciences, Physical Sciences, or Engineering or a combination of college coursework and related work experience or a biotech certificate from approved program - You have at least 5 years of GMP manufacturing experience, preferably working with antibodies therapies, with at least 2 years in a leadership role - You have an in-depth knowledge of manufacturing bioprocessing techniques and experience in the creation and revision of SOPs and manufacturing batch records - You have experience ensuring the timely execution and review of procedures, batch documentation, logbooks, deviations, CAPAs, change controls, and completion of ERP orders - You are passionate about building and implementing a "Right First Time" culture to meet cGMP requirements for clinical material **What we offer** AbCellera’s hiring range for this role is CAD $86,900 - $108,600 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution. You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find we prioritize teams and social groups to build community and connections across AbCellera. **About AbCellera** AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology. And it all starts with our team. We’ve built a place where people feel they are part of something bigger than themselves. A place that exists to push the limits of science and technology, and aims to bring better therapies to patients. We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success. LI-EM1 LI-MS
