Principal Scientist

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

**Job Summary**

As a **Principal Scientist** for the **Immunochemistry**Department located in** Ville Saint-Laurent,** you will be supporting non-clinical and clinical studies requiring measurement of therapeutic oligonucleotides in biological matrix using hybridization ELISA technique.

In this role, primary **responsibilities**include

• Design, write, review and edit, as necessary, study plans, amendments and study schedules that define and schedule all study activities.
• Oversee and coordinate all aspects of study related Laboratory Sciences procedures, whether performed within the department or by service departments.
• Ensure that relevant projects are performed according to standard operating procedures (SOPs) and Good Laboratory Practice (GLP) regulations, and are aware of regulations published by the FDA, EPA, JMHW and OECD.
• Write, review and edit, as necessary, stand-alone and contributing Scientist draft and/or final reports that document all study related procedures and results.
• Prompt verbal or written communications with Study Directors and/or Sponsors on study related business and generate and distribute Client Interaction Reports (CIRs) in a timely manner.
• Ensure the accuracy and completeness of project cost estimates.
• Review and approve raw data.
• Attend scientific meetings, symposia or workshops at the discretion of the Executive Director, Laboratory Sciences North America and/or Principal Director, Laboratory Sciences and publish or present results of the research whenever possible.
• Assist in the design of study packages and be able to provide advice to Study Directors and Sponsors on Laboratory Sciences issues.
• Assist in maintaining laboratory documentation to a satisfactory standard, satisfying the requirement of GLP, as required. This includes preparing, reviewing, updating, issuing,SOPs and Guidance Documents.

**Key Elements**

We are looking for the following minimum **qualifications**for this role

• Education: Ph.D., M.Sc. or B.Sc. in chemistry or a related discipline.
• An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.

**Role Specific Information**

• Location: 7170 rue Frederick-Banting, Ville St-Laurent / Free Parking
• Annual bonus based on performance;
• Schedule: Monday to Friday, 8am to 4:15pm;
• Permanent position as of the hiring, full-time 37.5hrs per week.

**Why Charles River?**

• Competitive benefits as of the hiring. We pay up to 85% of premiums (health & dental coverage);
• Free gym on site;
• Employee and family assistance program;
• Excellent welcome program for new employees as well as in-house advancement and career development opportunities;
• Access to a doctor and various health professionals (telemedicine);
• 4 weeks’ Vacation & 10 Personal day policy;
• Many social activities

If you are interested in contributing to the well-being of our communities, not only across the country but around the world, please join us. This is Your Moment.

**About Safety Assessment**

Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

**About Charles River**

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

At Charles River, we are passionate about our role in improving the quality of peopl