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Technician, Formulation Development

2 weeks ago

Etobicoke, Canada Apotex Inc. Full time

**About Apotex Inc.**

**Job Summary**:
Responsible for assisting in execution of early development, scale-up, stability, submission, placebo batches to develop new and modified product formulations, and for packaging - filling and/or sealing - quality pharmaceutical products in a variety of finished goods formats, for Apotex Inc. The Technician works and ensures that all operations are performed in accordance with applicable procedures. the Technician - RD 5 acts as a knowledge resource for other members in Formulation Development - New Products. The Technician is proficient at basic skills in Formulation Development, and builds on more advanced skills required for optimization of processes and troubleshooting required both for Packaging and batch execution in Formulation Development plant.

**Responsibilities**:

- Responsible to execute Manufacturing processes and Packaging Orders (PO) following the company SOD’s and regulatory requirements;
- Participates in operating the current Packaging equipment within specifications;
- Reconciles the Packaging orders with proper handling of components, bulk, and / or waste, following applicable procedure;
- Leads the sanitation process and participates in the equipment set-ups to ensure an effective and efficient operation changeover;
- Trains other Technicians on Packaging Equipment and Procedures as required;
- Conducts basic troubleshooting of the entire Packaging operations;
- Utilizes SAP system to obtain and enter necessary information with accuracy;
- Performs In Process testing as requires (Particle size analysis, Bulk / Tap Density, Disintegration, Flowability and Moisture analysis tests as required.
- Execute and assist to execute Process Evaluation, Process Optimization, and Submission batches as required.
- Weighs, mixes, screens and blends raw materials to produce experimental trials, pilot and small-scale batches for compressed, enteric coated, and film coated tablets, capsules, pellets, powders, liquids and others as required.
- Dismantles, cleans, sanitizes and assembles, as required, F.D. rooms and equipment according to established procedures to ensure GMP compliance and meet schedule requirements.
- Performs in-process quality tests on trials and production batches for weight, hardness, thickness, friability, disintegration, etc. as required.
- Maintains in-process testing lab in a compliant manner.
- Completes and signs off all process documentation required during the execution of a batch.
- Records observations on product and process characteristics during experimental trials and production batches, e.g. powder flow, capping, sticking, binding, filling, picking, etc. as required.
- Recognizes out of normal situations and uses conventional problem-solving skills to troubleshoot problems, provides feedback to the supervisor, and seeks assistance as required.
- Assists, as required, with troubleshooting and training on manufacturing and F.D. equipment and processes.
- Reviews trial and batch documentation for correctness and completeness before forwarding to Supervisor.
- Delivers in-process samples to designated area.
- Deducts raw materials from inventory where required
- Maintains the quality of all packaging documentation (paper & electronic) and reduces the cycle time;
- Performs quality checks, following relevant procedures;
- Interacts with In-Process Quality Assurance members (IPQA / QAIP), and participates in continuous improvement initiatives;
- Works in a safe manner collaborating as a team member to achieve all outcomes.
- Demonstrate Behaviours that exhibit our organizational Values: Collaboration, Courage, Perseverance, and Passion.
- Ensure personal adherence with all compliance programs including the Global Business Ethics and Compliance Program, Global Quality policies and procedures, Safety and Environment policies, and HR policies.
- All other relevant duties as assigned.

**Job Requirements**:

- **Education**
- Grade 12 education or recognized equivalent. Diploma or in Chemistry, Pharmaceutical Technology, Engineering, or related science would be an asset
- **Knowledge, Skills and Abilities**
- Experience with product optimization an asset. Proven ability to provide, understand, and follow verbal and written work instructions without errors.
- Ability to understand and achieve quantitative and qualitative standards;
- Able to meet the standard physical demands in a Packaging and Formulations Development environment, including ability to lift up to 25 kg.
- **Experience**
- Minimum 3 years of packaging / manufacturing process experience in the pharmaceutical and / or food industry

At Apotex, we are committed to fostering an inclusive, accessible work environment, where all employees feel valued, respected and supported.

Apotex offers accommodation for applicants with disabilities as part of its recruitment process. If you are contacted to arrange for an interview or testing, please advise us if you require an accommodation