Research Associate- R&d Chemistry
1 week ago
**Location**:Calgary, Alberta
**Type of Employment**:Permanent - Full time
**About Us**:
Northern RNA Inc. is a Canadian CDMO specializing in the production of nucleic acid products that support life-enabling work. Our goal is to work alongside our customers to provide scalable manufacturing capacity and to help them accelerate innovation in bringing their products from benchtop to bedside or field.
**About Our Opportunity**:
**Primary Responsibilities**:
- Conduct multi-step synthesis and optimization through effective reaction planning under the direction of research scientist/scientists.
- Utilize modern synthetic strategies to design and execute synthesis of unknown organic molecules.
- Ability to conduct isolation, purification and characterization of synthesized compounds using modern chromatographic techniques, including but not limited to ion exchange chromatography, flash chromatography, preparative LC, crystallization, etc.
- Conduct analysis and characterization of unknown organic compounds using TLC, HPLC, 1H NMR, 31P NMR, LCMS, GCMS, etc.
- Support analytical characterization of ongoing and new compounds to ensure consistent quality requirements are met.
- Work closely with colleagues to scale up ongoing and new products.
- Maintain a high level of scientific integrity, safe and productive laboratory environment laboratory safety.
- Accurately document experiments and results in laboratory notebooks in a timely fashion.
- Maintain appropriate standards for lab safety and hazardous material management.
- Resourceful, Proactive, and able to work under minimum supervision.
- Working in a laboratory environment under the supervision of a Senior Scientist
- Data analysis, interpretation, and documentation in development reports
- Utilize analytical instrumentation (HPLC / LCMS) for product analysis and characterization.
- Track progress against project timelines, generate regular status updates, and communicate progress and issues to management, including presentation of findings at team meetings
- Satisfactorily complete all assigned training in compliance with departmental requirements and follow appropriate safety practices in the workplace
- May perform other related duties as assigned.
**Education, Work Experience, Knowledge, and Skills**:
**Formal Education**:
- Master's Degree in Organic/Medicinal/Pharmaceutical Chemistry or related field. Bachelor's Degree a holder are welcome to apply, with at least 2+ years related lab experience.(Organic Chemistry focused)
**Work Experience**:
- Technical experience and understanding of chromatographic purification systems (e.g., AKTA Pilot, AKTA Pure, biotage etc.) and techniques (AEX, SEC, flash) is essential.
**Knowledge and Skills**:
- Hands-on experience in analytical techniques such as HPLC, NMR, LC-MS, other Mass spectroscopy techniques.
- Experience in optimizing small scale chemical reactions to enable multi gram synthesis is an asset.
- Effective at working with a diverse team of internal and external collaborators.
- Familiarity with industry standard chemistry-specific software.
- Strategic thinker with sound technical skills, analytical ability, good judgement, and strong operational focus.
**Working conditions**:
- Physical environment: Follow Standard operating procedures, documentation and working under aseptic conditions
- Physical effort: Must meet physical requirements of the position, including walking, standing, or sitting for extended periods, operating tools, and equipment, lifting heavy objects etc. Must be able to lift 50 lbs.
- Sensory Attention: This position requires recording experiment observations, data analysis, data interpretation, decision making, attention to details, interdepartmental data communication and data transfer.
- Mental Pressures: This position requires working on projects with tight deadlines, coordinating with different departments and multiple tasks.
**What we offer?**
We offer a highly competitive salary and company-paid benefits. Additionally, there are excellent opportunities for learning and growth while working alongside our teams of experts who are bright, collegial, and highly motivated and who are on the cusp of the mRNA vaccine science and technology era.
**Benefits**:
Northern RNA Inc. offers its employees a wide range of benefits such as Health, Dental, Health and Wellness Spending Account, Basic Life Insurance, General Illness (Short-Term Disability and Long-Term Disability), Vacation, Performance Bonus, on-site parking and Accidental Death and Dismemberment.
**Additional Information**:
- Northern RNA Inc. requires all new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Northern RNA Inc. will consider requests for Reasonable Accommodations.
Northern RNA Inc. is committed to a diverse and inclusive workplace. Northern RNA Inc. is an equal opportunity employer and does not discriminate on the basis of race, religion,
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