Lcms/ms Tech Specialist
2 weeks ago
**LC-MS/MS Technical Specialist**
**Position Summary**:
Under the direction of the LC-MS/MS Team Leader, performs the set-up and conduct of analytical projects (validation and study) using LC-MS/MS equipment.
**Duties and Responsibilities**:
- Completes complex and highly specialized projects and bio studies related to LC-MS/MS analysis in APCI or Electrospray modes with positive and negative ion detection using multiple LC-MS/MS instruments and platforms.
- Conduct basic preventive maintenance and repair, troubleshooting of all LC-MS/MS instruments in the department to ensure smooth operations.
- Maintain strong knowledge and understanding of supporting instrument software and computer systems.
- Processes bioanalytical runs and completes applicable paperwork in a timely manner and provides to the production supervisor.
- Responsible for ensuring the maintenance schedule for all LC-MS/MS instruments is followed
- Responsible person for coordinating repairs and service appointment with instrument vendor and/or third party service technicians
- Works independently, with broad latitude, in determining work activities to meet established objectives.
- Has excellent problem solving skills. Solves complex and difficult problems where additional research is necessary. Shows innovation on an ongoing basis to assists in solving problems related to any bioanalytical and instrument related problems (Events and Quality Incident Reports)
- Provides advice, guidance and advanced level training to bioanalytical chemists.
- Provides a sound knowledge of other laboratory equipment.
- Assists in developing and reviewing Standard Operating Procedures.
- Produces results and reports, in compliance with current applicable Standard Operating Procedures, for submissions to Canadian and International regulatory agencies.
- Demonstrates excellent written and oral communication skills.
- Provides information with some need for interpretation in dealing with external inquiries.
- Performs the job in a cost effective and safe manner, complying with all relevant safety procedures and requirements.
- Performs the job according to an approved Protocols and applicable GLP (OECD), EMEA, ICH, FDA and TPD requirements.
- Exhibits good interpersonal skills, a professional attitude and motivation to produce consistently high quality work.
- Performs other related duties assigned by the management.
In addition to General Responsibilities, the following are additional responsibilities in regards to the conduct of GLP and Non-GLP studies:
- Generates analytical test results in compliance with all current SOPs, protocols, study plans and applicable GLP (OECD), EMA, ICH, FDA and TPD requirements.
- Documents and communicates any deviations to these instructions directly to the Principal Investigator (for GLP studies) or Study Director (for Non-GLP studies).
- Records raw data promptly and accurately and in compliance with the OECD Principles of Good Laboratory Practice.
- Exercises health precautions to minimise risk to him/herself and to ensure the integrity of the study. Communicates to the Laboratory Management any relevant known health or medical condition so he/she can be excluded from operations that may affect the study.
**Qualifications**:
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