Research Scientist

2 months ago

Vancouver, British Columbia, Canada AbCellera Full time $75,200 - $94,000
Research Scientist - Computational Structural Biology

AbCellera is a pioneering biotech company that discovers and develops antibody-based medicines to improve human lives. We are seeking a highly motivated Research Scientist to join our team and contribute to our cutting-edge research in computational structural biology.

Key Responsibilities:
  • Design, implement, and evaluate in-silico protein engineering activities to support our developing platform for antibody reformatting processes and optimization of therapeutic assets.
  • Collaborate with a diverse team of scientists, engineers, and data analysts to develop and implement computational tools and methods for protein structure prediction and design.
  • Develop and maintain a comprehensive understanding of protein structure, function, and dynamics, as well as computational methods for protein engineering and design.
  • Stay up-to-date with the latest advancements in computational structural biology and apply this knowledge to improve our research and development processes.
Requirements:
  • PhD in Biochemistry, Biophysics, Structural Biology, Computational Biology, Computer Science, or a related field, or a MSc with 5+ years of related experience in a biological research setting.
  • Excellent programming skills in Python, as well as a comprehensive understanding of techniques to perform in-silico protein structure design using tools such as Rosetta software suite.
  • Working knowledge of antibody structure and function, and familiarity with techniques applicable to the molecular design, engineering, and experimental evaluation of antibody and/or antigen libraries for protein engineering purposes.
  • Awareness of experimental analytic and biophysics techniques used for antibody characterization, e.g. size exclusion chromatography (SEC), hydrophobic interaction chromatography (HIC), capillary electrophoresis (CE), light scattering (DLS, MALS), differential scanning calorimetry (DSC), isoelectric focusing (IEF), surface plasmon resonance (SPR), etc.
What We Offer:
  • A competitive salary range of CAD $75,200 - $94,000 annually, commensurate with your education and job-related knowledge, skills, and experience.
  • Equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.
  • A CAD $1,500 annual Active Lifestyle Allowance, annual vacation, opportunity for flexible work arrangements, professional development opportunities, and comprehensive health benefits.
  • Scientific and technical mentorship is a priority, and we prioritize teams and social groups to build community and connections across AbCellera.

AbCellera is a global company that discovers and develops antibody-based medicines to help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.

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