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Research Scientist

2 months ago

Markham, Ontario, Canada fluidigm Full time
Job Description

Research Scientist (Polymer & Bioconjugate Chemistry)

We are seeking a highly motivated Research Scientist (Polymer & Bioconjugate Chemistry) to join our exciting mass cytometry team based in Markham, ON.

Key Responsibilities
  • Work with minimal supervision to invent new reagents for mass cytometry.
  • Review the literature and devise scientific plans.
  • Synthesize reagents: Polymer synthesis and post-polymerization modifications; organic & inorganic synthesis.
  • Characterize reagents by chemical analytical methods (e.g. GPC, NMR, etc.).
  • Conjugate reagents to biomolecules such as antibodies.
  • Use reagents and conjugated biomolecules to stain cells or tissue in bioanalytical assays (suspension or imaging mass cytometry); acquire, process, and interpret the bioanalytical data.
  • Carry out all work with an eye towards making a practical, viable product.
  • Document the feasibility of new reagents (invented by the candidate or by others) through written reports that include protocols, manufacturability considerations, and all other relevant information.
  • Contribute to existing product scale-up and to addressing product performance issues.
  • Be a point of contact for and collaborate with academic collaborators.
  • Submit written invention disclosures to the IP department.
  • Contribute original research and literature review presentations to group meetings.
  • As needed, write and submit original research papers to peer-reviewed journals, and/or present posters and oral presentations at research conferences.
  • Be the expert user and trainer for a few key pieces of laboratory equipment.
  • Work with a cross-functional team of scientists and engineers from across all major fields.
Requirements
  • A PhD in chemistry or related field.
  • Proven ability (in graduate school or industry) to incisively solve technical problems.
  • Lead and complete projects.
  • Experience with polymer synthesis and post-polymerization modification. Organic and inorganic synthesis is an asset.
  • A variety of chemical and polymer characterization techniques.
  • Chemical modification of biomolecules and the purification of the resultant bioconjugates.
  • The use and care of complex analytical instrumentation, for example ICP-MS, HPLC.
  • Flow cytometry, suspension mass cytometry, and/or imaging mass cytometry is an asset, but not required.
  • Ability to read, interpret, and author technical procedures/protocols for laboratory equipment and experiments. General scientific writing and presentation skills.
  • Familiarity with Design Control, ISO 13485, and/or regulatory environment is an asset.
  • Excellent organizational and communication skills to enable multi-tasking in a fast-paced environment. Attention to detail is essential. Collaborative attitude and a team player.
  • The ability to relocate to the Greater Toronto Area.