Principal Bioinformatics Scientist II

3 weeks ago

Mississauga, Ontario, Canada F. Hoffmann-La Roche AG Full time
Unlocking the Power of Next-Generation Sequencing

At Roche, we're pushing the boundaries of healthcare innovation. Our team of bioinformatics experts is seeking a talented Principal Bioinformatics Scientist II to join our NGS Algorithms and Applications team.

As a key member of our team, you'll collaborate closely with assay scientists, software engineers, and other bioinformatics scientists to develop cutting-edge algorithms for next-generation sequencing technologies. Your expertise in NGS data analysis, algorithm development, and statistical modeling will be instrumental in driving our research forward.

Key Responsibilities:

  • Lead the development of novel algorithms for NGS data analysis, including read processing, variant calling, and annotation.
  • Collaborate with cross-functional teams to design and implement production-level algorithms in an Agile environment.
  • Present research findings internally and externally through peer-reviewed publications and conference proceedings.
  • Transfer algorithms to production teams and provide scientific support for updates and maintenance.

Requirements:

  • PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Mathematics, or a related field.
  • 7+ years of industry or post-doc experience in designing novel algorithms for NGS data analysis.
  • 2+ years of experience in developing novel algorithms, complexity analysis, and statistical modeling.
  • Proficiency in programming languages such as C++ in a distributed Linux environment.
  • Experience with workflow management systems like Nextflow or Snakemake, Docker, and cloud computation resources.

Preferred Qualifications:

  • First or co-first author publication in a high-impact peer-reviewed journal.
  • Experience with machine learning or deep learning in the context of NGS.

Roche is an equal opportunity employer and welcomes applications from diverse candidates. We offer a dynamic and collaborative work environment, with opportunities for professional growth and development.

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