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Scientist I Research

2 months ago

Vancouver, British Columbia, Canada AbCellera Full time $141,600 - $177,000
Principal Scientist - Oncology

AbCellera is a global company that discovers and develops antibody-based medicines to improve human lives. We are seeking a highly motivated Principal Scientist with a strong oncology and immunology background to join our team.

Key Responsibilities:
  • Contribute to the assessment and development of antibody-based oncology drug candidates to move programs faster and with less risk to the clinic.
  • Lead internal preclinical in vivo oncology models to support oncology programs.
  • Design, support, and interpret pharmacology studies to generate in vivo proof-of-concept and build confidence in selection of molecules for clinical development.
  • Collaborate with in vitro biology, protein engineering, and pharmacokinetics scientists, as well as external CROs and collaborators, to execute efficient PK/PD studies to identify lead molecules and advance programs to human trials.
  • Mentor team members in laboratory techniques related to tumour xenograft models.
  • Report findings to internal program teams and partners to support data-driven decisions.
  • Evaluate available preclinical and clinical data sets to build testable biological hypotheses for oncology targets and then preclinically assess those hypotheses.
Requirements:
  • 10+ years of hands-on experience in oncology, immuno-oncology, and biologics drug development.
  • PhD in pharmacology, immunology, or related field, plus 10+ years of experience in a biopharmaceutical industry setting.
  • Excellent communication skills to convey scientific and technical concepts with an emphasis on application.
  • Ability to independently identify project needs and follow up with constructing and implementing solutions.
  • Enjoy working on complicated biological questions and building data sets that help predict the success of therapies.
What We Offer:
  • CAD $141,600 - $177,000 annually, commensurate with education and job-related knowledge, skills, and experience.
  • Equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.
  • CAD $1,500 annual Active Lifestyle Allowance, annual vacation, opportunity for flexible work arrangements, professional development opportunities, and comprehensive health benefits.