Scientist I

4 days ago


Vancouver, British Columbia, Canada Danaher - Global Full time

Danaher – Global is a leading global life sciences company dedicated to accelerating the real-life impact of tomorrow's science and technology. Our team is passionate about harnessing the power of science to bring life-changing results for our customers and patients.

Overview

We are seeking a talented Analytical Development Specialist to join our Biopharma Services team in Vancouver, BC Canada. As a key member of our team, you will be responsible for utilizing advanced mass spectrometry and chromatography skills to support ongoing and upcoming client programs.

This role reports to the Senior Manager I, Analytical Development and involves collaborating with cross-functional teams to deliver high-quality analytical results. You will have the opportunity to work on challenging projects, develop new analytical methods, and contribute to the development of innovative nanomedicines.

Responsibilities:

  • Independently perform advanced and specialized bio-analytical techniques, including UHPLC-CAD, UHPLC-PDA, SEC, CE, and LC-MS to provide insights into nanomaterials such as Lipid Nanoparticles (LNPs), liposomes, or polymeric nanoparticles.
  • Translate analytical expertise to innovate novel capabilities supporting the pre-clinical development of LNP and nanomedicines.
  • Oversee the operation, maintenance, and troubleshooting of liquid chromatography, mass spectrometry, and/or capillary electrophoresis instrumentation.
  • Contribute to efficient lab operations such as record keeping, inventory management, resource allocation, procurement, and associate training.
  • Prepare detailed and accurate analytical reports to share internally or with clients as well as maintain appropriate lab records and documentation.
Qualifications

To succeed in this role, you should possess a PhD or MSc in Biochemistry, Chemistry, Pharmacy or related field with a minimum 2 years' industry experience. You should also have extensive liquid chromatography experience with HPLC- (UV, ELSD, CAD), LC-MS, LC-HRMS, and/or LC-MS/MS.

A proven track record of analytical method development and assay suitability testing as per ICH/ FDA/ EMA guidelines is essential. Additionally, you should have deep and diverse expertise in biomolecule (E.g. Nucleic Acids, proteins, mABs), lipid, and excipient (Buffers, stabilizers, etc.) chemistry, ideally relating to Lipid Nanoparticles.



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