Scientist I, Formulation Development Specialist

2 months ago

Toronto, Ontario, Canada BlueRock Therapeutics Full time
About the Role

BlueRock Therapeutics is seeking a highly skilled Scientist I to join our team in the development of cryopreservation procedures and methodologies for various iPSC-derived cell therapy products and intermediates.

Key Responsibilities
  • Design and Execute Cryoformulation and Fill/Finish Development Experiments: Collaborate with team members to design, execute, and interpret cryoformulation and fill/finish development experiments, utilizing fundamental cryobiology and first principles.
  • Evaluate and Integrate Cutting-Edge Technologies: Evaluate and integrate cutting-edge technologies into the cellular therapy cryopreservation process, identifying meaningful process parameters and applying suitable analytics for enhanced efficiency and effectiveness.
  • Perform Technology Transfer: Perform technology transfer of the cryopreservation process to cGMP-compliant manufacturing facilities within the company or to CDMO partners.
  • Prepare Experimental Proposals and Reports: Prepare experimental proposals, standard operating procedures, technical protocols, and reports while interacting in a cross-functional environment.
  • Analyze and Document Experimental Data: Analyze and document experimental data in electronic laboratory notebooks in a timely and accurate manner in accordance with the company quality management system.
  • Prepare and Present Scientific Data: Prepare and present scientific data in internal and external forums.
  • Train and Supervise Staff Members: Train and supervise staff members in supporting cryopreservation-related activities.
Minimum Requirements
  • Education: MSc. degree in a Biological Science, such as Biochemistry, Immunology, Molecular Biology, or similar.
  • Experience: MSc. 9+/ PhD 0-2 years of experience, preferably in an industry setting.
  • Skills and Knowledge: Hands-on expertise in developing cryopreservation processes and broad knowledge in cryobiology are required. Understanding and experience of molecular techniques such as cell imaging, flow cytometry, or qPCR and ddPCR is required. Experience with data processing and statistical analysis software tools is required. Practical knowledge of experimental design (DoE) is desired.
  • Personal Qualities: Ability to plan experiments and independently execute complex tasks. Strong English written and verbal communications skills. Proficiency in technical scientific writing. Ability to work in a fast-changing environment. Collaborative team player.

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