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Postdoctoral Researcher in Cellular Signaling

2 months ago

Montreal, Quebec, Canada Centre de recherche de l\'Hôpital Maisonneuve-Rosemont Full time

About Our Research Team

The research team led by Dr. Affar is focused on understanding the mechanisms of cellular signaling through ubiquitination and its dysregulation in cancer. Ubiquitination is a reversible process mediated by deubiquitinases (enzymes that specifically remove ubiquitin from target proteins). Our goal is to characterize the biological functions and mechanisms of action of deubiquitinases involved in transcription and DNA repair, two processes whose dysregulation plays a fundamental role in cancer development. Currently, our team is particularly interested in the tumor suppressor gene BAP1, a gene frequently mutated in certain types of cancers. We use cutting-edge biochemical, molecular biology, and cell culture approaches to characterize the functions of deubiquitinases.

About Our Research Group

The research group of Dr. El Bachir Affar is seeking highly motivated postdoctoral researchers. Candidates must have a PhD in molecular biology or biochemistry or a related field, organizational skills, and a strong interest in cellular signaling and molecular oncology.

Key Responsibilities

  • Conduct research on cellular signaling and molecular oncology
  • Characterize the functions of deubiquitinases
  • Contribute to the development of new research projects

What We Offer

The Centre de recherche de l'Hôpital Maisonneuve-Rosemont offers a dynamic and collaborative research environment, with access to state-of-the-art facilities and equipment. We provide a competitive salary and benefits package, as well as opportunities for professional development and growth.