Director of Operations

Updated: December 10, 2025
Location: Toronto, ON, Canada
Job ID:25104281-OTHLOC-1510-2DR

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We continuously look for ways to simplify and streamline our work to make Syneos Health easier to work with, and to make us easier to work for.

When you join us in either a Functional Service Provider partnership or a Full‑Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate about changing lives.

Work here matters everywhere

- We are passionate about developing our people through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and a total rewards program.

- We are committed to our Total Self culture – where you can authentically be yourself. Our culture unites us globally, and we are dedicated to taking care of our people.

- We continuously build the company we all want to work for and our customers want to work with. When we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we create a place where everyone feels like they belong.

Job Responsibilities

The Director of RWLP Operations is a strategic, client‑facing leader responsible for driving operational excellence across real‑world and late‑phase research portfolios. This role ensures successful delivery of peri‑ and post‑approval studies while fostering account growth and long‑term client partnerships. Acting as a subject‑matter expert and operational strategist, the Director provides end‑to‑end oversight—from RFP/proposal development to portfolio execution—ensuring integrated, cost‑effective solutions aligned with client objectives.

- Lead cross‑functional teams to deliver complex, global RWLP programs on time and within budget.

- Oversee all aspects of assigned client accounts, including governance, risk management, financial performance, and strategic planning.

- Partner with internal and external stakeholders to identify evidentiary needs and deliver tailored operational solutions.

- Ensure alignment of delivery with regulatory standards (ICH, GCP, GPP) and Syneos Health SOPs.

- Support business development through proposal strategy, bid defenses, and capability presentations.

- Drive operational efficiency, quality, and innovation through lessons learned, process improvement, and cross‑BU collaboration.

- Provide strong real‑world research acumen, proven operational leadership, and a commercial mindset.

Qualifications

- 10–12 years of clinical research experience, with 8–10 years in RWLP.

- Direct experience with large‑scale RWLP programs and client portfolio oversight.

- Strong financial and contract management skills.

- Prior CRO/pharma experience in cross‑functional, global environments.

- Excellent communication, team leadership, and stakeholder management capabilities.

- May have direct reports and is expected to travel up to 25% of the time.

Benefits

At Syneos Health, we provide an environment and culture where people can thrive, develop, and advance. Benefits for this position may include a company car or car allowance, health benefits (medical, dental, and vision), company match 401(k), eligibility to participate in an Employee Stock Purchase Plan, potential commissions/bonuses based on company and individual performance, and flexible paid time off and sick time. Please note that paid sick time eligibility may vary depending on jurisdiction.

Salary Range

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on candidate qualifications, skills, competencies, and proficiency for the role.

Legal Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. The Company is committed to compliance with the Americans with Disabilities Act and offers reasonable accommodations.

Get to Know Syneos Health

- Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 studies across 73,000 sites and 675,000+ trial patients.

Summary

The Director of RWLP Operations is a strategic, client‑facing leader responsible for driving operational excellence across real‑world and late‑phase research portfolios, ensuring successful delivery of peri‑ and post‑approval studies while fostering account growth and long‑term client partnerships.

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