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Postdoctoral Research Fellow in Plant Biochemistry

1 month ago

University of British Columbia Okanagan campus, Canada University of British Columbia Full time

Academic

Job Category

Faculty Non Bargaining

Job Title

Postdoctoral Research Fellow in Plant Biochemistry

Department

UBCO | Research Support Dang | Department of Chemistry | Irving K. Barber Faculty of Science (Thu Thuy Dang)

Posting End Date

January 1, 2024

Note: Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.

Job End Date

Feb 28, 2025

Postdoctoral Research Fellow

Plant BioCoRe Lab

Department of Chemistry, Irving K. Barber Faculty of Science

University of British Columbia

Kelowna, BC, Canada

The Plant Bioactive Compounds Research (Plant BioCoRe) group, lead by Dr. Thu-Thuy Dang, integrates biochemistry, chemistry, bioinformatics, and molecular genetics to elucidate and engineer the biosynthesis of valuable small molecules from medicinal plants. Our ultimate aim is to learn and translate natural metabolism into innovative biotechnologies to meet the ever-increasing demands of high-value chemicals. Our current projects involve discovering biosynthetic enzymes and pathways, generating alkaloid structural and functional diversities, and re-constituting natural product metabolism in synthetic biology chassis.

Plant BioCoRe is located on the Okanagan Campus of the University of British Columbia, a close-knit yet fast-growing community right in the heart of the beautiful Okanagan valley.

We support inclusivity and equity. We seek qualified applicants from all backgrounds (cultural, gender, racial, etc.) to ensure that our team gets the best talents and reflects the diversity of our campus.

PROJECT: Elucidation of alkaloids biosynthetic pathway in plants

POSTDOCTORAL RESEARCHER IN PLANT BIOCHEMISTRY

Closing date: December 31, 2023

Expected starting date: March 1, 2024 or as soon as thereafter

Starting salary: CA$ 45,000 - 52,000

Hours per week: 40 hours

Duration: 12 months (renewable depending on performance and funding availability)

Job description: The postdoctoral researcher will conduct research into the elucidation of alkaloid biosynthetic pathways from medicinal plants. Duties include experimental design, method development (molecular biology, enzymology, biochemistry, bioinformatics, LCMS, HPLC), data collection, and data interpretation and presentation. The postdoctoral researcher will be working independently and in the team under the supervision of the line manager (Dr. Thu-Thuy Dang), and collaborating with colleagues from the group as well as other research groups.

The postdoc will be responsible for day-to-day management of the project including experimental planning and execution, data collection and analysis, discussion and presentations in various meetings (lab meetings, conferences, workshops, etc.), report/publication writing, and related duties. The position holder is also expected to supervise, train, and advise students and other junior lab members, as well as deliver guest lectures. The postdoctoral researcher will be working independently and in the team under the supervision of the line manager (Dr. Thu-Thuy Dang), and collaborating with colleagues from the group as well as other research groups. The post holder will be advised by the principal investigator, Dr. Thu-Thuy Dang, in regular one-to-one meetings and relevant discussion channels.

ACTIVITY SUMMARY- Planning and performing experiments, collecting and analyzing data, troubleshooting, and planning further works: 70%- Preparing and submitting manuscripts for publication, presentations to internal as well as national and international audiences: 10%- Undertaking training: 5%- Training junior lab members, discussing/advising colleagues, teaching: 10%- Other relevant duties agreed with the PI: 5%

**REQUIREMENTS**:
- Education: PhD (fully awarded or expected within 6 months) in one of the following disciplines: biochemistry, molecular biology, metabolic engineering, synthetic biology, plant biology, and biological chemistry, microbiology.
- _essential_)- Knowledge in specialized (secondary) metabolism and alkaloid biosynthesis
- _essential_).- Expertise in enzymology, molecular biology, biochemistry, microbiology, and analytical chemistry- Genomic and transcriptomic analysis (essential)-
- Gene cloning and plasmid construction (essential)-
- Protein expression and purification in plant and microbes (essential)-
- Enzyme
- _in vivo_ and
- _in vitro_ assays (essential)-
- Small-molecule compound extraction and purification from various systems (essential)-
- HPLC, LC-MS, GC-MS, TLC skills (essential)- Excellent understanding of plant specialized metabolism (essential)- Proven ability to carry out innovative research with publishable outcomes- Evidence of intellectual independence, rigour and creativity (essential)-
- Relevant first-author publications in high-caliber peer-reviewed journals (essential)-
- Excellent organization and record keeping skills (essential)- Good communicative, collaborative, and interpersonal skills:
- Oral presentation experience to academic

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