Postdoctoral Fellow

1 week ago

Burnaby, Canada Amgen Full time

**HOW MIGHT YOU DEFY IMAGINATION?**

You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

**Postdoctoral Fellow - Machine Learning Modelling of Protein-Protein Interactions from Large Datasets**:
**Live**:
**What you will do**

Let’s do this. Let’s change the world. This is an opportunity to join Amgen’s Therapeutic Discovery Biologics organization as a Postdoctoral fellow. In this vital role, you will be using Machine Learning to build computational models from large datasets generated via structural biology techniques, such as Cryo-EM, to elucidate the dynamics of protein-protein interactions. You will be embedded in a technologically diverse team, working with leading biotechnology and machine learning experts to solve some of the most difficult problems in large molecule discovery. You will also have the opportunity to lead writing manuscripts, publish in leading journals, and present data in internal and external settings including oral and poster presentations at scientific conferences.

The postdoctoral fellow will have two co-mentors who lead Amgen’s efforts in Cryo-EM and AI/ML for Biologics, respectively.

The postdoctoral fellow will:

- Develop methods to learn finite-state models of the dynamics of molecular interactions from Cryo-EM image data.
- Develop active learning strategies to prioritize molecular dynamics simulations to enhance those models.
- Collaborate with cross-functional interdisciplinary teams of scientists
- Work with software engineers to deploy these methods
- The postdoctoral fellow will also receive personalized training in relevant areas of Machine Learning or Structural Biology, as needed.

**Win**:
**What we expect of you**

We are all different, yet we all use our unique contributions to serve patients. The Scientist professional we seek is an innovative leader with these qualifications.

**Basic Qualifications**:

- Doctorate degree in a quantitative field

**Preferred Qualifications**:

- Experience working in high performance computing environments
- Strong proficiency in programming
- Excellent communicator able to write and speak about technical concepts to business, technical, and lay audiences
- Experience building machine learning models from complex data sets
- Experience working with Cryo-EM data relevant to drug discovery
- Experience with computational structural biology and molecular modeling
- Experience with cloud (AWS, GCP, DGX Foundry) computing
- Experience with advanced machine learning methods, such as active learning and deep learning

**Thrive**:
**Some of the vast rewards of working here**

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
- Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey
- A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
- Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

**for a career that defies imagination**

Objects in your future are closer than they appear. Join us.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

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