Research Associate Ii, Process Development

2 months ago

Toronto, Canada BlueRock Therapeutics Full time

**Responsibilities**:

- Support project planning, experimental design, and hands-on laboratory execution of process development work for cell banking and upstream manufacturing.
- Support evaluation of new cell culture methods, raw materials, analytics and automation for cell banking and upstream manufacturing.
- Support tech transfer of evaluated process improvements and analytical methods to GMP Manufacturing, Analytical Development and Quality Control functions.
- Perform cell culture procedures including thawing, passaging, expanding and cryopreserving hPSC lines.
- Perform laboratory molecular techniques (e.g. DNA/RNA extraction, qRT-PCR, flow cytometry) and various cell characterization assays and determine experimental outcomes.
- Collect and analyze data in electronic laboratory notebooks from cell processes, various assays, then track and trend data, and establish specifications for process characterization and control.
- Present scientific data to colleagues in small and large group meetings and forums, prepare and present internal and external presentations (presentations, posters, publications).
- Author, review and approve SOPs, study protocols, technical reports, slide decks, and other scientific and quality documents.
- Perform additional duties to support the safe and efficient operation of the laboratory, and other duties as assigned.

**Minimum Requirements**:

- An MSc in Biology, Biochemistry, Biomedical Sciences or related field with 0-3 years of industry or relevant academic experience, or a BSc in Biology, Biochemistry, Biomedical Sciences or related field with 2-5 years of industry or relevant academic experience.
- A minimum requirement of 3 years of experience in aseptic culture technique, maintaining hPSCs or other mammalian cell types and related laboratory experience.
- Experience with cell characterization assays (primarily molecular biology-based) is required.
- Experience in culturing and characterizing hPSCs is highly advantageous.
- A proven ability to be highly productive and successful in a high pace work environment with excellent attention to details and meticulous bench work
- Cooperating with a larger team, must be able to solve a wide range of complex problems in creative and practical ways
- Self-motivated and willing to accept temporary responsibilities outside of initial job description
- Competency in computer skills and familiarity with Microsoft Office programs (Word, Excel, PowerPoint)
- Excellent interpersonal, verbal and written communication skills
- Comfortable in a fast-paced small company environment with mínimal direction and able to adjust workload based upon changing priorities
- Shares relevant information openly and seeks appropriate input from others outside of the direct team; develops and maintains effective cross-functional working relationships and partnerships; responds positively and constructively to requests for support from across the organization.

**Work Environment**:

- In this position you will work in controlled laboratory environments which requires the use of personal protective equipment. There is a risk of potential exposure to chemicals and biohazards in the context of cell therapy.

**Equal Opportunity Workplace**:

- At BlueRock, we welcome and support differences and diversity and we are proud to be an equal opportunity workplace. Please let us know if you require disability-related accommodation or other grounds protected by human rights legislation during the recruitment process so that we can work with you to meet your needs.

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**Perks and Benefits**:

- Health & Wellness- _
- Dental Insurance- _
- Vision Insurance- _
- Health Insurance- _
- Life Insurance- _
- Gym Membership / Reimbursement- Paid Time Off- _
- PTO / Vacation Policy- _
- Paid Holidays- _
- Maternity / Paternity Leave- Financial Benefits- _
- 401K / Retirement Plan- _
- Performance Bonus- Office Perks- _
- Unique Office Space- _
- Work From Home Policy- _
- Company Social Outings- _
- Free Food

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