Bioinformatician - Karsan

Staff - Non Union
Job Category
M&P - AAPS
Job Profile
AAPS Salaried - Research and Facilitation, Level A
Job Title
Bioinformatician - Karsan
Department
Karsan Laboratory | Department of Pathology and Laboratory Medicine | Faculty of Medicine
Compensation Range
$5,365.42 - $7,709.92 CAD Monthly
The Compensation Range is the span between the minimum and maximum base salary for a position. The midpoint of the range is approximately halfway between the minimum and the maximum and represents an employee that possesses full job knowledge, qualifications and experience for the position. In the normal course, employees will be hired, transferred or promoted between the minimum and midpoint of the salary range for a job.
Posting End Date
November 27, 2024
**Note**: Applications will be accepted until 11:59 PM on the Posting End Date.
Job End Date
Nov 30, 2025
The anticipated start date for this position is December 1, 2024. The term is for one year with the possibility of extension.
At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career.
Job Summary
Dr. Aly Karsan's research is focused on understanding the molecular basis of the blood cancers called myeloid leukemias, determining how aging related changes - including inflammation - increase leukemic risk, dissecting how distinct populations within a single leukemia interact with each other, and using this knowledge to unravel the mechanisms that make these leukemic cells resistant to therapy. His lab also works on determining how signals in the embryo direct the endothelium to transdifferentiate into blood stem cells that become the source of all blood cells through an organism's life.
The Karsan Lab is seeking a bioinformatician to conduct scientific research in the areas of bioinformatics and genomics, specifically related to biological sequence analysis and annotation in support of cancer research. The successful applicant will take a leadership role in planning, designing, and implementing bioinformatic data pipelines to meet objectives of research project. The individual also will support research scientists and possibly supervise research trainees in a team environment to analyze data from various cancer types, as well as from mouse models of human disease.
Organizational Status
This position will report to the lead bioinformatician in the Karsan lab as well as the principal investigator, Aly Karsan, MD.
Work Performed
Assessment and usage of bioinformatic tools for various "-Omics" data types, various types of single cell sequencing data, including variant-calling, epigenomics, proteomics, RNA-seq, miRNA-seq.
Updating research specimen inventories, including associated clinical data.
Adheres to existing methodologies for reproducible bioinformatics analysis.
Prepare statistical analysis report to determine significance and, analytical sensitivity and specificity of obtained results.
Planning, design and implement bioinformatic data pipelines to meet objectives of the project.
Design and implement robust computational workflows.
Supports research staff by providing analysis and data interpretation, including writing reports of results in accurate and concise language.
Assists in preparation of grants and other funding/project related documents as needed.
Interacting with research collaborators or clinical study teams as required.
Contributions to the writing of research publications.
Consequence of Error/Judgement
Work will be discussed with the Senior Bioinformatician, Staff Scientist, and Laboratory Manager, on a regular basis. The successful applicant will be responsible for errors in their work, for reporting problems and mistakes in a timely way, and for correcting those errors. Errors will impact on the whole project and the work of other researchers, losing valuable research time and money.
Supervision Received
The PI and Senior Bioinformatician will jointly supervise the successful applicant's output. A probationary review will be conducted six months from hiring, and annual reviews will be undertaken thereafter.
Supervision Given
May be involved in the management and supervision of trainees.
Minimum Qualifications
Undergraduate degree in a relevant discipline. Minimum of two years of related experience, or an equivalent combination of education and experience.
- Willingness to respect diverse perspectives, including perspectives in conflict with one's own
- Demonstrates a commitment to enhancing one's own awareness, knowledge, and skills related to equity, diversity, and inclusion

Preferred Qualifications
Graduation from a recognized Bachelor of Science Program in Bioinformatics, Biological Sciences, Statistics, Engineering, or Computer Sci