Molecular Mechanisms Involved in The Maintenance of

2 months ago

Laval, Canada Institut National de la Recherche Scientifique Full time

**Molecular mechanisms involved in the maintenance of CD4 T cells during chronic infections**:

- Réf **ABG-126532**
- Sujet de Thèse- 28/10/2024- Financement public/privé- Institut National de la Recherche Scientifique- Lieu de travail- Laval - Canada- Intitulé du sujet- Molecular mechanisms involved in the maintenance of CD4 T cells during chronic infections- Champs scientifiques- Biologie
- Mots clés- CD4 T cells, mice, Toll-like receptors, transcription factor, progenitor-like cells**Description du sujet**:
La personne sélectionnée étudiera la régulation transcriptionnelle responsable pour la différentiation et la maintenance de certaines sous-populations de lymphocytes T CD4 dans différents tissus pendant des infections chroniques dans la souris.

**Prise de fonction**:

- 08/01/2025**Nature du financement**:

- Financement public/privé**Précisions sur le financement**:

- Fonds de Canadian Institutes of Helath Research**Présentation établissement et labo d'accueil**:

- Institut National de la Recherche ScientifiqueThe lab research interest lies on the cellular and molecular mechanisms regulating the development and maintenance of host immunity during infection. Examples of our past work include Swaminathan et al., Cell Reports 2024, Carmona-Pérez et al, JCI Insight 2023; Fabié et al, Cell Reports 2018; Hammami et al, PLoS Pathogens 2017; Silva-Barrios et al, Cell Reports 2016.

Le laboratoire s’intéresse principalement aux mécanismes cellulaires et moléculaires qui gouvernent le développement et la maintenance de la réponse immunitaire de l’hôte pendant des infections. Pour quelques exemples de travaux du laboratoire voire Swaminathan et al. 2024, Carmona-Pérez et al, JCI Insight 2023; Fabié et al, Cell Reports 2018; Hammami et al, PLoS Pathogens 2017; Silva-Barrios et al, Cell Reports 2016.

**Site web**:
**Intitulé du doctorat**:

- Virologie et Immunologie**Pays d'obtention du doctorat**:

- Canada**Etablissement délivrant le doctorat**:

- INRSWe are seeking dynamic, collaborative, and highly motivated individuals with a specific interest for immunology and infectious diseases.- Prior lab experience in the following approaches is an asset:
- Animal work
- Bioinformatics/genomic analysis
- Flow cytometry

Nous cherchons une personne dynamique, motivée, capable de travailler en équipe et avec un intérêt spécifique pour l’immunologie et les maladies infectieuses.- De l’expérience avec les approches suivantes serait un atout:
- Travail avec les souris
- Analyse bioinformatique/génomique
- Cytométrie en flou- 30/11/2024

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