Bioinformatician Ii

**Position: Bioinformatician II**
**Location: MaRS Centre, Toronto**
**Department: Genome Sequence Informatics**
**Reports To: Manager, Genome Interpretation**
**Salary: Commensurate with level of experience**

**Hours: 35 hours/week**
**Job Type: Hybrid**
**Status: Full-Time, Permanent**

OICR is Ontario’s cancer research institute. We bring together people from across the province and around the world to improve the lives of everyone affected by cancer. We take on the biggest challenges in cancer research and deliver real-world solutions to find cancer earlier and treat it more effectively. We are committed to helping people living with cancer, as well as future generations, live longer and healthier lives.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Colleges and Universities.

**Position responsibilities include**:

- Interrogating tumour genomes for clinically reportable and actionable variation that can be used in clinical trials.
- Preparing clinical reports for sign-off by Canadian College of Medical Geneticist (CCMG) board-certified Geneticists.
- Researching and developing cutting-edge techniques and software for future incorporation into the clinical bioinformatics pipeline.
- Developing tools/software to evaluate performance and statistical validation of clinical sequencing data.
- Writing detailed documents describing results of investigations, assay validations, proficiency testing, analysis and laboratory protocols, and standard operating procedures for clinical assays and accreditation.

***Qualifications**:

- Master’s (MSc) in related discipline, with demonstrated experience in a scientific discipline, preferably in bioinformatics, oncology, genetics, molecular biology or equivalent education or work experience.
- Demonstrated experience interpreting data generated from best-practice pipelines for analyzing NGS data, such as variant calling pipelines for genome and transcriptome sequencing.
- Knowledge of NGS data processing tools (samtools, GATK, IGV, etc).
- Proficiency working with large-scale datasets in a Unix environment.
- Proficiency with a scripting and/or statistical analysis language is preferred (Python, R).
- Must have excellent written communication and interpersonal skills.


To learn more about working at OICR, visit our career page.

**CLOSING DATE: Until Filled**
- The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted._