Associate Scientist Protein Production

3 weeks ago

Toronto, Canada Phenomic AI Full time

**Company Overview**:
Phenomic AI is revolutionizing cancer care by developing innovative medicines that target the tumor stroma—a critical barrier that hinders the effectiveness of current cancer treatments. Using machine learning and advanced data analysis, we accelerate the discovery of novel therapies. Despite advancements in cancer treatment, breast, colorectal, pancreatic, and other solid tumors still pose challenges for long-term responses to therapy. With our extensive single-cell RNA datasets and cutting-edge deep-learning tools, Phenomic AI leads the development of next-generation stroma-targeted medicines. Our mission is to improve patient outcomes for stromal-rich tumors, including pancreatic, colorectal, lung, ovarian, and breast cancers.

**Position Overview**:
Phenomic AI is seeking a highly skilled and motivated scientist to support biologics production, characterization, and optimization of biotherapeutics. This is an exciting opportunity to be part of a dynamic team in a fast-paced, rapidly growing biotech company with a bold vision.

**Location**:
Toronto, ON

**Major responsibilities**
- Execute in-house production and characterization of multi-specific antibodies for biochemical/biophysical screening and in vitro/vivo functional studies.
- Perform biophysical properties assessment of diverse biologics molecules including chemical stability, solubility, polyspecificity and polyreactivity.
- Contribute to antibody/nanobody lead discovery efforts by executing high-throughput screening campaigns.
- Interpret results and present/communicate with cross-functional colleagues for successful execution and completion of projects.
- Stay scientifically current and contribute to the implementation of new technology and instrumentation.
- Ensure effective and timely documentation in electronic laboratory notebooks.

**Qualifications**
- B.S. or M.S. in biochemistry, structure biology, biomedical engineering, or other life science disciplines + 5 years of relevant experiences
- Skilled in protein expression in mammalian cells and protein purification using various chromatography methods and instruments such as AKTA FPLC.
- Experience with protein analytic techniques such as HPLC/UPLC, SLS/DLS, and BLI/SPR based protein-protein interaction characterization is a plus.
- Experience pre-clinical development of antibody-based biotherapeutics is preferred.
- Excellent written and oral communication, organization, and data analysis skills. Outstanding troubleshooting and problem-solving skills.
- Highly adaptable to a fast-paced work environment and capable to work both independently and collaboratively within project teams.

Schedule:

- Monday to Friday

**Education**:

- Bachelor's Degree (preferred)

Ability to Commute:

- Toronto, ON M5S 1R8 (required)

Work Location: In person

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