Radiopharmaceutical Technologist

2 weeks ago

Chalk River ON, Renfrew County, ON; Ontario, Canada Canadian Nuclear Laboratories Full-time

Are you looking for a role that will challenge you and allow you to contribute to advancing radiopharmaceuticals and targeted cancer therapies as a Radiopharmaceutical Technologist ? Can you see yourself working alongside an experienced team of scientists and technologists to support radiolabelling chemistry, product testing, radioanalytical analysis, and preclinical research in a dynamic and growing Contract Research Organization? At CNL's Chalk River Laboratories, you'll play a key role in delivering innovative commercial and R&D projects that advance isotope production and the development of safe, targeted radiotherapeutics in Canada. If you answered yes, this may be the job for you—apply today

What will you be doing

  • Supporting the development and testing of radiopharmaceuticals through radiolabelling, analytical testing, stability studies, and preclinical research activities.
  • Preparing and executing experimental protocols related to radionuclide production, purification, radiochemistry, and in vitro/in vivo evaluations.
  • Performing conjugation chemistry, radiolabelling, and stability testing using a variety of radionuclides and targeting vectors.
  • Conducting radiochemical analyses using techniques such as Radio‑TLC, Radio‑HPLC, ICP‑MS, and gamma counting, while preparing accurate data reports.
  • Setting up, calibrating, operating, troubleshooting, and maintaining specialized radiochemical and analytical laboratory equipment.
  • Utilizing laboratory software and customized spreadsheets to support data collection, calculations, analysis, and reporting.
  • Developing, updating, and adhering to Standard Operating Procedures (SOPs) and quality assurance requirements.
  • Preparing chemical solutions, managing laboratory inventories, and overseeing the safe handling and disposal of chemical and radioactive waste.
  • Analyzing experimental results and contributing to technical reports for internal stakeholders and external clients.
  • Maintaining accurate laboratory records and documentation in accordance with regulatory and quality standards.
  • Identifying and implementing innovative applications of equipment, procedures, and laboratory processes.
  • Supporting procurement activities by sourcing laboratory equipment and coordinating with vendors and suppliers.
  • Collaborating with multidisciplinary teams to coordinate research activities and support project objectives.
  • Ensuring compliance with laboratory, facility, safety, and quality assurance regulations and requirements.
  • Other duties as assigned by your manager.

What We Are Looking For

  • Education
    • Graduation from a recognized institute of advanced technology, or equivalent formal education in a field relevant to the position, such as radiochemistry, inorganic chemistry, analytical chemistry, forensics, biochemistry, chemical engineering technology and normally has six (6) to eight (8) years of pertinent technological experience, OR;
    • Secondary School Graduation Diploma or equivalent and ten (10) to twelve (12) years of pertinent and progressive experience or the equivalent in experience, additional education and/or training.
  • Experience
    • 6-8 years of relevant hands‑on work experience in a radiochemistry laboratory is preferred.
    • Experience working with radioactive compounds (e.g., one or more among quantification, identification, separation, purification, radiolabelling) is a significant asset.
    • Experience performing R&D or production work in engineered enclosures (fume hoods, glove boxes, hot cells) is an asset.
    • Experience maintaining laboratory notebooks, electronic data, and physical records within a research or production Quality Management System.
    • Experience in preparing experimental procedures and technical reports.
    • Experience navigating and working under the principles of Integrated Work Control (IWC) or other work hazard control program.
    • Experience with in vitro cell culture and aseptic techniques.
    • Experience with in vivo radiopharmaceutical testing is an asset.
    • Work experience with radiation safety principles is desired (CNL specific training will be provided).
    • Experience with conjugation and radiolabelling chemistry of a range of isotopes.
    • Experience with chemical separation techniques for metal ions, including co‑precipitation, column chromatography separation, solvent extraction etc.
    • Experience with Radio‑TLC and Radio‑HPLC, and with similar chromatographic techniques and/or MS and ICP‑MS.
    • Experience with radiation detectors, gamma spectrometry, alpha spectrometry, liquid scintillation counters, and similar radiation‑counting equipment is desirable.
  • Knowledge, Skills & Abilities
    • Abi