Director, Portfolio Strategy

5 days ago

Vancouver, British Columbia, Canada Abdera Therapeutics Full time
Who We Are

We are a precision oncology company developing next-generation targeted radiation therapies- one of the most cutting-edge and highly promising areas of drug development. The company is built on a proprietary modular technology platform optimized for the delivery of radioisotopes to selectively destroy tumor cells while sparing healthy cells. We are using this platform to enable the rapid development of a broad range of safe and efficacious therapies serving cancer patients with limited treatment options.

We are growing rapidly and seeking key new team members who thrive at the cutting-edge of innovation. Come join us and be a part of the ground-breaking team set to unlock the power of targeted radiotherapy

What We Look For

We are looking for curious and committed individuals who are ready for the opportunity to transform the way people living with cancer can be treated. We are relentless in our focus to offer new hope to families facing devastating diagnoses. We are in search of team members who work collaboratively with a diverse group of colleagues, respectfully engaging one another while collectively and inclusively tackling any challenges we may face. We are building an exciting and fast-paced company passionate about discovering and developing tomorrow's most innovative cancer therapies.

We have one opening for this role. The candidate may reside in Vancouver, British Columbia or San Francisco Bay Area

Principal Responsibilities
  • Develops program strategy for programs within our portfolio.
  • Accountable for TPP development to feed into global Clinical Development Planning (CDP) by assessing the market & the required endpoints given evolving SoC and emerging new therapies. Synthesizes competitive movements into implications for our programs and communicates to key internal stakeholders. Collaborates with colleagues across functions including Clinical, Medical, and Regulatory. Collaborate with Business development to develop pertinent external-facing communications regarding potential CDP and future positioning.
  • Monitor industry trends, emerging technologies, and competitor activities to inform strategic decision-making. When appropriate, attends key scientific conferences to stay abreast of the clinical landscape in each indication of interest.
  • Identifies and engages with KOLs in our indications of interest, developing relationships with clinicians to gather insights, validate assumptions, and identify potential advisors or clinical trial investigators.
  • Support advisory board discussions and/or blinded market research with HCPs via the creation of discussion guides and/or potential facilitation.
  • Develops recommendations for indications for FIH imaging and/or therapeutic studies, leveraging target expression biology in the literature, relevant geographic epidemiology, and the patient perspective (disease severity and progression), collaborating with others in Research & Clinical as appropriate.
  • Serve on 1 or more program Core Teams to provide NPP perspective.
  • Create NPP roadmap for Abdera, elucidating when in a program's lifecycle various relevant activities/assessments need to be conducted and/or capabilities need to be brought in-house.
  • Supports portfolio strategy decision-making by evaluating all programs (Discovery thru Clinical) across key scientific, clinical & commercial criteria to assist in portfolio prioritization efforts as/if needed, ensuring alignment with company's overall business objectives and market opportunities. Contribute to regular portfolio reviews.
  • As needed, support target selection process for future internal program declaration efforts; supports research team in finding relevant data from the literature and highlighting key factors around target biology & validation. Assesses potential targets across biologic, clinical, and commercial criteria.
  • Stay abreast of new potential therapeutic targets, via the literature, competitive intelligence, and/or scientific conferences.
  • As needed, support evaluation of any potential in-licensing assets using our playbook of key criteria across biology/scientific validation, clinical/regulatory, and commercial categories. Develop business case via market and competitive landscape analyses.
  • Accountable for accurate forecasting, tracking and adherence to budget; supports departmental budget and LRP processes.
Qualifications, Education & Experience
  • Minimum of 10 years of relevant experience in the life sciences, biotechnology, or pharmaceuticals.
  • Must have experience in supporting the R&D process for biologics and have a deep understanding of biological pathways, pre-clinical and clinical drug development processes.
  • Oncology experience required; biologic experience preferred.
  • Advanced degree in life sciences or medicine (PhD, MD, pharmacology or similar) with relevant research or clinical experience is strongly preferred. Alternatively, an MBA with relevant program strategy experience will also be considered.
  • Experience in strategic planning, portfolio management and new product planning as well as working in cross-functional teams is required.
Competencies and Skills
  • Ability to adapt to changing business environments and market conditions.
  • Flexibility to manage unexpected challenges and capitalize on new opportunities.
  • Technical proficiency and familiarity with tools and software used in portfolio management and new product planning including ability to find, and interpret relevant primary life science publications covering basic, pre-clinical, and/or clinical research.
  • Ability to distill and communicate the 'so what' from the insights generated.
  • Teamwork & collaboration: involves key internal stakeholders and experts, builds rapport and trust, takes accountability, listens and partners effectively.
  • Resourceful and independent but also asks for help when needed.
  • Drives for results efficiently and effectively, and exercises sound judgment.
  • Right-sizes the approach for the outcome needed.
  • The individual will be a self-starter with excellent leadership, communication, organizational skills, and the ability to build strong rapport across functions.
  • Highly organized and adept at prioritizing and managing multiple, often complex, tasks simultaneously, integrating cross-functional issues, and balancing competing priorities effectively.
  • Ensures quality and timeliness of deliverables, is dependable, and holds oneself accountable.
  • Ability to thrive in a fast-paced, innovative, and, at times, uncertain or changing environment while remaining flexible, proactive, and resourceful.
  • Excellent analytical, problem solving and critical thinking skills, including an ability to combine attention to detail with a big picture perspective.
  • Contributes to building a positive team spirit; supports everyone's efforts to succeed; gives and solicits feedback; shares expertise with others.
  • Strives for continuous improvement; assesses one's strengths and areas for development, and pursues opportunities to enhance knowledge and skills.
  • Treats people with respect; Inspires the trust of others; Works with integrity and ethically; Upholds organizational values.
Technical Skills
  • MS Office Suite (Powerpoint, Excel, Word, etc).
  • PubMed and other literature search tools.
  • SEER and other epidemiology databases.
  • Oncology Pipeline, Global Data, and/or other CI tools and databases.
  • HGS, HPA, and similar databases regarding target biology & protein expression preferred.
At Abdera, we know that attracting and retaining top talent is crucial to our success. That's why we're committed to offering competitive compensation and comprehensive benefits tailored to your needs.

Here's what you can expect when you join our team in Vancouver:
  • Competitive Base Pay: Our expected base pay range for this position is $175k - $215k (CAD), plus performance-based bonuses.
  • Comprehensive Benefits: Health, dental, and vision insurance to ensure your well-being, as well as RRSP to help secure your financial future.
  • Personalized Pay: Your individual pay will be determined by your job-related skills, experience, and relevant education or training, ensuring you receive fair and competitive compensation.
  • Work-Life Balance: Generous paid time off, including vacation, holidays, and sick time, because we believe that balance is key to long-term success and happiness.
At Abdera, we value our employees and strive to create an environment where you can thrive both professionally and personally. Join us and be part of a company that cares about your growth and well-being.

We are an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit harassment of any kind and any form of discrimination including but not limited to discrimination based on race, color, sex, religion, marital status, sexual orientation, national origin, disability, veteran status, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.

This is applicable to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, training, and apprenticeship.
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