Postdoctoral Research Fellow in Plant Biochemistry
1 month ago
Note: Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.
Job End DateJul 31, 2025
per year
Postdoctoral Research FellowPlant BioCoRe Lab
Department of Chemistry, Irving K. Barber Faculty of Science
University of British Columbia
Kelowna, BC, Canada
The Plant Bioactive Compounds Research (Plant BioCoRe) group, led by Dr. Thu-Thuy Dang, integrates biochemistry, chemistry, bioinformatics, and molecular genetics to elucidate and engineer the biosynthesis of valuable small molecules from medicinal plants. Our ultimate aim is to learn and translate natural metabolism into innovative biotechnologies to meet the ever-increasing demands of high-value chemicals. Our current projects involve discovering biosynthetic enzymes and pathways, generating alkaloid structural and functional diversities, and re-constituting natural product metabolism in synthetic biology chassis.
Plant BioCoRe is located on the Okanagan Campus of the University of British Columbia, a close-knit yet fast-growing community right in the heart of the beautiful Okanagan Valley.
We support inclusivity and equity. We seek qualified applicants from all backgrounds (cultural, gender, racial, etc.) to ensure that our team gets the best talents and reflects the diversity of our campus.
PROJECT: Engineering of alkaloid biosynthetic pathway in plants and microbes
POSTDOCTORAL RESEARCHER IN PLANT BIOCHEMISTRYC
Closing date: June 2nd, 2024
Expected starting date:August 1st or September 1st, 2024
Starting salary: CA$ 25, ,000
Hours per week: 20 hours
Duration: 12 months
Job description: The postdoctoral researcher will conduct research into the elucidation and engineering of alkaloid biosynthetic pathways from medicinal plants. Duties include experimental design, method development (molecular biology, enzymology, biochemistry, bioinformatics, LCMS, HPLC), data collection, and data interpretation and presentation. The postdoctoral researcher will be working independently and in the team under the supervision of the line manager (Dr. Thu-Thuy Dang), and collaborating with colleagues from the group as well as other research groups.
The postdoc will be responsible for day-to-day management of the project including experimental planning and execution, data collection and analysis, discussion and presentations in various meetings (lab meetings, conferences, workshops, etc.), report/publication writing, and related duties. The position holder is also expected to supervise, train, and advise students and other junior lab members, as well as deliver guest lectures. The post holder will be advised by the principal investigator, Dr. Thu-Thuy Dang, in regular one-to-one meetings and relevant discussion channels.
ACTIVITY SUMMARY
- Planning and performing experiments, collecting and analyzing data, troubleshooting, and planning further works: 70%
- Preparing and submitting manuscripts for publication, presentations to internal as well as national and international audiences: 10%
- Undertaking training: 5%
- Training junior lab members, discussing/advising colleagues, teaching: 10%
- Other relevant duties agreed with the PI: 5%
REQUIREMENTS
- Education: PhD (fully awarded or expected within 6 months) in one of the following disciplines: biochemistry, molecular biology, metabolic engineering, synthetic biology, plant biology, and biological chemistry, microbiology. ( essential)
- Knowledge in specialized (secondary) metabolism and alkaloid biosynthesis ( essential).
- Expertise in molecular biology, biochemistry, microbiology, and analytical chemistry
- Gene cloning and plasmid construction ( essential)
- Protein expression and purification in plants and microbes ( essential)
- Enzyme in vivo and in vitro assays (essential)
- Small-molecule compound extraction and purification from various systems ( desirable)
- HPLC, LC-MS, GC-MS, TLC skills ( desirable)
- Good basic bioinformatic and general computer skills, and proven ability to learn and apply new skills ( essential)
- Excellent understanding of plant specialized metabolism ( essential)
- Proven ability to carry out innovative research with publishable outcomes
- Evidence of intellectual independence, rigour and creativity ( essential)
- Relevant first-author publications in high-caliber peer-reviewed journals ( essential)
- Excellent organization and record keeping skills ( essential)
- Good communicative, collaborative, and interpersonal skills:
- Oral presentation experience to academic audiences at national and international meetings ( essential)
- Good team working skills with proven ability to collaborate with internal and external colleagues with publishable outcomes ( essential)
- Ability to train colleagues and students for laboratory and other research skills ( essential)
- Proven ability to teach/deliver lectures to various audiences ( essential)
- Experience working with diverse groups of colleagues and/or clients ( desirable)
- Additional requirements:
- Ability to accept and value equity and diversity, and to accept the expected values for staff members at UBC ( essential)
- Attention to details ( essential)
- Willingness to work outside standing working hours when needed ( desirable)
- Willingness to travel including taking overseas trips for collaboration and/or conference purposes ( essential)
All qualified and interested candidates are encouraged to submit their application package that includes:
- CV/Resume
- Cover letter/Research statement
- 3 referees
to Dr. Thuy Dang via by June 2nd, 2024.
We encourage all qualified applicants to apply; however, due to the large number of applicants, only suitable applicants are contacted and invited for interview. Qualified applicants will be invited for an interview by June 15, 2024.
Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.
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