Bioinformatics Analyst

1 week ago

Mississauga, Ontario, Canada Compest Solutions Inc Full time

Statistical Bioinformatics Analyst

Rate CAD$/hr. on Inc/Corp to Corp
Responsibility for data processing, annotation, and statistical analysis for Biomarker data within the assigned project.

Qualifications

  • Ph.
D. or MSc in Computer Science, Statistics, Computational Biology, or related field with 5+ years of experience.

  • Excellent indepth knowledge of
    public genetic and genomic databases such as TCGA and COSMIC
:

  • Excellent knowledge of database and
    strong R/Python programming skills with experience of software packages for genetic annotation.
  • Experiences in
    NGS read processing, variant calling, variant annotation, and analyzing largescale genetic datasets.
  • Familiar with software development,
    cloud computing infrastructures and project management tools such as
    JIRA/Azure DevOps, Github, and Docker
:

  • Demonstrated interpersonal, presentation and communication skills.

Duties and responsibilities

  • Design and implement bioinformatic analyses and support development of analysis pipelinefor clinical submissions.
  • Model and analyze large scale Next generation sequencing (NGS)data with rigorous bioinformatics and statistical approaches.
  • Standardize and harmonize multivendor genetic data using standard human genome sequence variant nomenclature, such as, HGVS.
-
Annotate standardized vendor NGS sequencing genetic data based on public genetic database, such as COSMIC, and reference papers:

  • Understand clinical trial objectives, design, endpoints and procedures defined in Protocoland
    Statistical Analysis Plan (SAP) and perform endtoend analysis from data QC to final delivery.
  • Provide statistical programming and validation support to create analysis datasets, TLFs and relevant documentation as per the specifications within set timelines.
  • Closely collaborate within Biomarker project and statistical team within the assigned scope of work
  • Maintain relevant documentation for the programming and validation tasks within the assigned scope of work.

Regards,



Compest Solutions Inc

Job Type:

Fixed term contract

Contract length: 12 months

Salary:

$55.00-$60.00 per hour

Schedule:

  • 8 hour shift

Experience:

Statistical Bioinformatics Analyst: 10 years (preferred)

  • Biomarker data: 10 years (preferred)
  • TCGA: 10 years (preferred)
  • COSMIC: 10 years (preferred)
- public genetic and genomic databases: 10 years (preferred)
- strong R/Python programming: 10 years (preferred)

  • SAS and/or

SQL:
10 years (preferred)

  • NGS read processing: 10 years (preferred)
- software development, cloud computing infrastructures: 10 years (preferred)

  • Azure DevOps: 8 years (preferred)
  • Docker: 8 years (preferred)
  • Github: 9 years (preferred)
  • Design and implement bioinformatic analyses: 9 years (preferred)
- clinical trial: 9 years (preferred)
Statistical Analysis Plan: 10 years (preferred)

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