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Staff Scientist

3 months ago

Toronto, Ontario, Canada University of Toronto Full time

Date Posted:03/29/2023

Req ID:30501

Faculty/Division:
Faculty of Arts & Science

Department:
Acceleration Consortium

Campus:
St. George (Downtown Toronto)

Description:


The Acceleration Consortium received a $200M Canadian First Research Excellence Grant for seven years to develop self-driving labs for chemistry and materials, the largest ever grant to a Canadian University.

This grant will provide the Acceleration Consortium with seven years of funding to execute its vision.

The AC is developing seven advanced SDLs

These include:

  • Inorganic solidstate materials,
  • Organic small molecules for advanced materials,
  • Drug discovery with chemical probes,
  • Formulations for pharmaceuticals, consumer products, and coatings,
  • Biocompatibility (organonachip), and
  • Synthetic scaleup of materials and molecules.


We are hiring staff scientists to develop the hardware and software needs for each of these SDLs and to conduct research programs levering these labs for materials and molecule discovery.


The Staff Scientists involved in the AC are highly skilled and experienced researchers who will work independently to develop the AI and automation technologies required to build robust and scalable self-driving labs, manage these SDLs, and design and implement research programs (based on the direction of the AC's scientific leadership team) that leverage the SDL platforms to discover materials and molecules.

This role will report to the Academic Director and Executive Director of the Acceleration Consortium.

We are looking for individuals with diverse backgrounds and expertise to support the development of Self-Driving Labs and materials discovery.


The Staff Scientists will work with a diverse team of leading experts at the U of T, including: Alàn Aspuru-Guzik, Christine Allen, Cheryl Arrowsmith, Frank Gu, Jason Hattrick-Simpers, Anatole von Lilienfeld, Milica Radisic, Sophie Rousseaux, Florian Shkurti, Dwight Seferos, Dave Sinton, and Helen Tran.


Artificial Intelligence / Automation

  • Machine Learning for Molecules and Materials
  • Physical, theoretical and/or computational chemistry
  • Robotics
  • Experimental planning and design/optimal control
  • Programming and highperformance computing
  • Cheminformatics

Automated Chemical Synthesis and Characterization

  • Highthroughput materials synthesis and processing (polymers, inorganic and organic molecules (including lipids))
  • Nanomaterial synthesis and characterization
  • Polymer physics
  • Structural, electrochemical, and microstructural characterization of materials and molecules
  • Screening electrocatalytic conversion
  • Analytical chemistry and separation method development
  • Chemical reactions and analytics
  • GLP formulation skills
  • Electrochemistry
  • Organic synthesis methodology development

Drug Discovery / Medicinal Chemistry

  • Medicinal chemistry
  • Protein biophysics/biochemistry
  • Mass spectrometry
  • Controlled release properties and processes

Organ on a chip / Organoid

  • Pluripotent stem cell differentiation
  • Molecular biology
  • Toxicology pharmacology

The components and duties of the work include:


  • SDL and Automation Development


Working with the AC community, including faculty and partners, to determine the required capabilities of the SDLs to be built.

Developing SDL plans to meet user requirements and designing novel instruments for automated material synthesis and characterization. Developing customized hardware and Python software packages to build SDLs. Selecting, procurement, and installation of the equipment required for SDLs.
- **Research Direction**Tasks include:
  • Managing the research and development projects of AC's industry partners when implemented in AC labs.
  • Developing plans supporting research collaborations and estimating financial resources required for programs and/or projects.
  • Working with Product Managers to ensure research outcomes meet partner requirements.
  • Promoting AC's research capacity, including delivering presentations at conferences.
  • Collaboration in preparing and submitting research proposals to granting agencies and progress reporting.
  • Preparing manuscripts for submission to peer review publications/journals and stewarding them through the process.

- **Other*
  • Support researchfocused events such as Annual Symposium

MINIMUM QUALIFICATIONS:

Education

  • Ph.
D. in Physical/Material Chemistry or related discipline

Experience

  • Five (5) years experience in research and development, preferably with significant experience in Physical, Material, Medicinal, and/or Analytical Artificial Intelligence for Chemistry.
  • Experience working with industry partners and on industry lead research and development projects.
  • Expert knowledge of AI and automation and experience with the development of Selfdriving Laboratories.
  • Experience presenting research at academic conferences
  • Demonstrated track record of academic and/or research excellence.
**