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The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground breaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada's largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.
Site: Princess Margaret Cancer Centre
Computational Biology and Medicine Program
Work Model: On-Site
To commensurate with experience and consistent with UHN compensation policy
Shifts: Monday - Friday
Permanent Full-time
The Princess Margaret Cancer Centre (PM), University Health Network (UHN), is the largest cancer centre in Canada, providing more patient visits and involving more cancer doctors and specialists than any other oncology centre in Canada. The Computational Biology and Medicine Program (CBMP) is home to scientists and clinicians interested in computational methods used to aggregate, analyze and share biomedical data for basic, translational and clinical research. Within CBMP, innovative computational methods and scientific software are being developed to investigate the biological processes involved in oncogenesis, cancer evolution and response to therapies.
We are looking for a Data Management Specialist to help grow the CBMP at the Princess Margaret Cancer Centre, and curate and track multimodal data analyzed in the program. The Data Management Specialist's main roles will include:
Working with CBMP labs to ensure that new data are cataloged with appropriate metadata at the time of collection.
Managing a program-wide data management system.
Monitoring use of internal storage space and deposition of data in public unrestricted and controlled-access repositories.
Training staff and trainees on data and metadata practices.
Researching, establishing, and documenting best practices for data organization and management.
Contributing to the development of the data management system.
Assisting researchers in cleaning, curating, and annotating CBMP data, ensuring published datasets adhere to the highest standards of data quality, including FAIR Data Principles, use of standards such as minimum information standards (such as MIAME and successors), NIH Common Data Elements, GA4GH standards, and linking identifiers such as Research Resource Identifiers (RRIDs).
Harmonizing data collected through various methods, including whole genome sequencing, RNA-seq, ChIP-seq, ATAC-seq, and other genomics data.
Facilitating data access applications, and secure transfer of large datasets, including those containing Patient Health Information, within UHN and with external research institutions.
Programming to improve interoperability and reliability in data management tasks.
Bachelor's degree or higher in computational biology, bioinformatics, genetics, or a related field and 2+ years work experience in computational genomics research; or master's degree or higher and 1+ years work experience
Experience programming in R, Python, or both.
Experience with analysis of high-throughput genomics data.
Master's or doctoral degree in computational biology, bioinformatics, data science, computer science, genetics, or related fields, preferred
Authorship of publications or preprints showing excellence in data management and sharing (specify how in cover letter), preferred.
Experience in commercial database management, preferred.
Familiarity with Java or C++, preferred.
Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP
) * A flexible work environment
Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)
Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.
All UHN Employees are required to be fully vaccinated with a COVID-19 vaccine series, approved by Health Canada or the World Health Organization, as a condition of hire. Proof of COVID-19 vaccination will be required. Should you be the successful candidate, you will be required to comply with UHN's mandatory Vaccination Policy that is in effect.
Requests for accommodation can be made at any stage of the recruitment process.
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