Scientist, Multi-Specific Antibody Discovery

Scientist‐Multi‑Specific Drug Discovery and Characterization (1 year Contract) Join Amgen’s mission of serving patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas—Oncology, Inflammation, General Medicine, and Rare Disease—we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award‑winning culture is collaborative, innovative, and science‑based. If you have a passion for challenges and the opportunities that lie within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. What You Will Do In this vital role you will join our Induced Proximity Platform (IPP) team in Burnaby to establish and discover novel multi‑specific antibody molecules. The Amgen IPP team specializes in emerging proximity‑based drug discovery for various Oncology, Cardiometabolic, and Inflammation targets. We seek to develop and apply targeted protein degradation approaches to control pathogenic membrane and secreted proteins using multi‑specific antibody molecules. The successful candidate will join a highly enthusiastic team of scientists to design, characterize, optimise, and discover multi‑specific large molecules. A competitive candidate will have a demonstrated track record of working and publishing high‑quality science in a related field and deep expertise in technical skills. Successful candidates must reside in the Greater Vancouver area. If you have a passion for cell‑based antibody testing and want to be part of an organization discovering new therapeutic modalities to impact patients’ lives, we invite you to join us Routinely conduct experiments using cultured mammalian cells and appropriate assays to characterise and optimise multi‑specific degrader antibody molecules. Perform quantitative assays for target and antibody internalisation, degradation and localisation using flow cytometry, imaging and other applicable techniques. Use multimode plate readers, fluorescence microscopes, flow cytometers. Manage research projects as needed, keep electronic records of experimental details, and present findings to cross‑functional teams. Basic Qualifications Doctorate degree OR Master’s degree & 2 years of directly related research experience OR Bachelor’s degree & 4 years of directly related research experience Preferred Qualifications Broad knowledge and understanding of cellular and molecular biology, familiarity with endo/lysosomal protein sorting and trafficking. Previous experience with in‑vitro testing and characterisation of antibody molecules or cellular mechanism of action studies. Significant experience with quantitative cell‑based assays and techniques including flow cytometry, microscopy and western blotting. Experience with generation of transgenic cell lines is a bonus. Excellent time‑management and organisation skills. Eager to work in teams and seek collaboration as required by the project to achieve project goals on time. What You Can Expect Of Us Amgen is proud to have been recognised as one of LinkedIn Top 25 Companies in Canada for career growth. The base salary range for this position in Canada is \$110,717 – \$140,299 CAD. In addition to the base salary, Amgen offers competitive and comprehensive total rewards plans that are aligned with local industry standards. Amgen is an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. How to Apply Apply now and make a lasting impact with the Amgen team. Contact: careers.amgen.com Equal Opportunity Statement Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. #J-18808-Ljbffr