Scientist-Multi-Specific Drug Discovery and Characterization

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist-Multi-Specific Drug Discovery and Characterization (1 year Contract)

Let's do this. Let's change the world. In this vital role you will join our Induced Proximity Platform (IPP) team in Burnaby to establish and discover novel multi-specific antibody molecules. The Amgen IPP team specializes in the emerging proximity-based drug discovery for various Oncology, Cardiometabolic, and Inflammation targets.

We seek to develop and apply targeted protein degradation approaches to control pathogenic membrane and secreted proteins using multi-specific antibody molecules. The successful candidate will join our highly enthusiastic team of scientists to design, characterize, optimize, and discover multi-specific large molecules. A competitive candidate will have a demonstrated track record of working and publishing high-quality science in a related field and have deep expertise in technical skills. We provide a well-resourced workplace for fast-paced, innovative science collaboratively. Successful candidates must reside in the Greater Vancouver area. If you have a passion for cell-based antibody testing and want to be part of an organization discovering new therapeutic modalities to impact patients' lives, we invite you to join us

• Routinely conduct experiments using cultured mammalian cells and use appropriate assays to characterize and optimize multi-specific degrader antibody molecules.
• Perform quantitative assays for target and antibody internalization, degradation and localization using flow cytometry, imaging and other applicable techniques.
• Use multimode plate readers, fluorescence microscopes, flow cytometers.
• Manage research projects as needed, keep electronic records of experimental details, and present findings to cross-functional teams.

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.

Basic Qualifications:

OR

Master's degree & 2 years of directly related research experience

Bachelor's degree & 4 years of directly related research experience

Preferred Qualifications:

• Broad knowledge and understanding of cellular and molecular biology, familiarity with endo/lysosomal protein sorting and trafficking.
• Previous experience with in vitro testing and characterization of antibody molecules or cellular mechanism of action studies.
• Significant experience with quantitative cell-based assays and techniques including Flow cytometry, Microscopy and Western Blotting.
• Experience with generation of transgenic cell lines is a bonus.
• Excellent time management and organization skills.
• Eager to work in teams and seek collaboration as required by the project to achieve project goals on time.

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

Amgen is proud to have been recognized as one of LinkedIn Top 25 Companies in Canada for career growth. Click HERE for more details.

The base salary range for this position in Canada is $110,717 - $140,299 CAD

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.