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Research Fellow, Genetics and Genome Biology

2 weeks ago

Toronto ON MG X, Canada The Hospital for Sick Children Full time $60,000 - $80,000 per year
About SickKids

Dedicated exclusively to children and their families, The Hospital for Sick Children (SickKids) is one of the largest and most respected paediatric healthcare centres in the world. As innovators in child health, we lead and partner to improve the health of children through the integration of healthcare, leading-edge research and education. Our reputation would not have been built - nor could it be maintained - without the skills, knowledge and experience of the extraordinary people who come to work here every day. SickKids is committed to ongoing learning and development, and features a caring and supportive work environment that combines exceptionally high standards of practice.

When you join SickKids, you become part of our community. We share a commitment and determination to fulfill our vision of Healthier Children. A Better World.

Don't miss out on the opportunity to work alongside the world's best in paediatric healthcare.

Position Description

We are seeking a Postdoctoral Research Fellow to join the research group of Dr. Robert Siddaway in the Department of Paediatric Laboratory Medicine and Genetics and Genome Biology program at the Hospital for Sick Children. We aim to understand the diverse molecular mechanisms that underlie human health and disease, leveraging fundamental discoveries to improve diagnostic decision-making and enhance outcomes in paediatric cancer and other conditions.

Our group is highly translational, with interests including alternative splicing (PMID: , epigenetic regulation (PMID: , , and development of novel methods to enhance precision molecular diagnostic testing (PMID: , ,

Here's what you'll get to do:

  • Design and conduct hypothesis-driven experiments and analyses
  • Analyze multi-omic data to investigate mechanisms driving the development and progression of, and treatment response in, paediatric cancer and other disorders
  • Develop experimental, computational, and statistical approaches that can be used in clinical molecular testing
  • Communicate findings through presentations at internal meetings and scientific conferences
  • Contribute to publications and grant applications
  • Mentor graduate and undergraduate students, as well as clinical trainees

Here's what you'll need:

  • A PhD in genetics, molecular biology, or a related discipline, with experience in computational biology and standard cell/molecular biology techniques
  • Experience with next-generation sequencing analysis (RNA-Seq, WGS, single-cell, long-read, etc.)
  • Proficiency in R and/or Python
  • Experience with high-performance computing
  • A record of publication in peer-reviewed journals, with at least one first-author paper in a relevant field
  • Preferred:
  • Background in cancer biology and/or genomics
  • Experience in diagnostic test development
  • Knowledge of machine learning and biostatistics
  • Personal attributes:
  • Detail-oriented, innovative, and scientifically curious
  • Able to lead project design and implementation
  • Strong team player who can work on collaborative projects and provide leadership and training for students and technical staff
  • Excellent communication in English (verbal and written), interpersonal and organizational skills
  • Demonstrated commitment and actions in advancing equity, diversity, and inclusion objectives.

Employment type: Full-time temporary 1 year contract with modified benefits (with potential to extend contract based on funding and performance)

Our Commitment to Diversity

SickKids is committed to championing equity, diversity and inclusion in all that we do, fostering an intentionally inclusive and culturally safe environment that reflects the diversity of the patients, families and communities we serve. Learn more about workplace inclusion.

Accessibility & Accommodation

If you require accommodation during the application process, please reach out to our aSKHR team. SickKids can provide access and inclusion supports to eligible candidates to support their full engagement during the interview and selection process as well as to ensure candidates are able to perform their duties once successfully hired. If you are invited for an interview and require accommodation, please let us know at the time of your invitation to interview. Information received related to access, inclusion or accommodation will be addressed confidentially.

How To Apply

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