Sr Scientist, Process Development

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description
Gilead Sciences in Edmonton, Alberta, Canada is seeking a knowledgeable and motivated professional capable of working effectively in a multi-disciplinary team environment. The successful candidate will assume a full-time employment role in the capacity of Senior Scientist, Process Development, in Gilead Alberta's Manufacturing Science and Technology (MSAT) department.

This individual will support Gilead's commercial small-molecule drug substance manufacturing at both internal and external manufacturing facilities. These activities will include chemical process development and optimization, process characterization, risk assessments, scale-down and scale-up studies. In addition, this individual will be responsible for process technology transfer and process validation activities, continued process verification and manufacturing investigations.
Job Responsibilities

• Responsible for developing chemical processes for the manufacturing of drug substances.
• Plans, designs, implements and analyzes laboratory experimentation to advance the knowledge of production and quality attributes of drug substances.
• Advises members of project teams in the initiation and execution of laboratory experimentation, considering various factors.
• In collaboration with more senior scientists or scientific directors, advances the development of economical, state-of-the-art techniques to isolate, characterize, purify and mass-produce substances.
• Prepares and reviews technical documents including research reports and process development reports.
• Acts as MSAT lead for one or multiple API projects. Experienced with manufacturing operations and responsible for supporting commercial manufacturing as technical subject matter expert.
• Monitors key manufacturing activities and manufacturing performance and provides regular updates. Proactively communicates issues and identifies improvement opportunities.
• Prepares and reviews manufacturing and transfer documents including contract manuals, batch records, continued process verification and validation protocols and reports.
• Leads technical transfers and process validation activities at internal and external manufacturing facilities
• Understands both quality and compliance principles associated with cGMP manufacturing
• Able to support investigation of manufacturing deviations, out-of-specifications and complaints
• Must think critically and creatively and be able to work independently, determine appropriate resources for resolution of problems and have strong organizational and planning skills.
• May make contributions to scientific literature and conferences through publication and presentation of research results.
• Demonstrates ability in developing methods, techniques and evaluation criteria for obtaining results and interpreting experimental outcomes.
• Demonstrates excellent communication skills (both verbal and technical) and strong interpersonal skills.
• Demonstrates collaborative communication and problem solving spirit

Basic Qualifications
PhD in Organic Chemistry (or related discipline) with 2+ years of industry experience

OR

MSc in Organic Chemistry with 6+ years of industry experience

OR

BSc in Organic Chemistry with 8+ years of industry experience

Preferred Qualifications

• Experience in planning and executing multi-step synthesis of organic molecules
• Experience scaling up synthetic routes and developing safe chemical processes
• Familiar with commercial scale production of API and intermediates in plant or pilot plant facilities
• Experience with technical transfer, cGMP and statistical process control.
• Knowledge of chemical engineering principles an asset
• Familiarity with purification and analytical techniques required for drug substance manufacturing
• Strong desire to work in multi-disciplinary teams, learn new skills and solve problems
• Excellent verbal and written communication skills, and strong interpersonal collaboration skills
• Must think critically and creatively and be able to work independently to determine appropriate resources for resolution of problems
• Strong organizational and planning skills

People Leader Accountabilities

• Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams.
• Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and realize their purpose.
• Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.

For Current Gilead Employees And Contractors
Please apply via the Internal Career Opportunities portal in Workday.