Research Assistant/technician 4

5 days ago

Vancouver, British Columbia, Canada UBC Full time

Research Assistant/Technician 4 position available in the Strynadka Laboratory, Department of Biochemistry and Molecular Biology, Faculty of Medicine, to support macromolecular sample preparation and infrastructure operation.

This role requires a university degree in a relevant discipline or technical program and a minimum four years of related experience. The successful candidate will be responsible for undertaking standard molecular biology and protein overexpression, purification procedures, operating and maintaining a 120 keV Talos TEM instrument, and overseeing logistical tasks.

Key responsibilities include:

• Undertake standard molecular biology and protein overexpression, purification procedures to create high yield, high purity proteins for structural biology applications.
• Operate, maintain, train users on a 120 keV Talos TEM instrument in both room temperature and cryo modes.
• Oversee, maintain, train users on a VitroBot and other vitrification equipment.
• Work with lab members and users to troubleshoot problems and answer queries.
• Oversee and perform logistical tasks including organizational tasks, equipment maintenance and oversight, user session scheduling, placing orders, handling liquid nitrogen, and tracking usage.
• Assist with lab and facility communication including website population and design and creation or update of standardized operational procedure documentation.

The incumbent will report directly to the Lab manager and the PI, Dr. Natalie Strynadka. The successful candidate will be expected to work independently with limited supervision and provide guidance and direction to faculty, staff and graduate/undergraduate students.

The ideal candidate will have:

• Completion of a university degree in a relevant discipline or technical program and a minimum four years of related experience.
• Willingness to respect diverse perspectives, including perspectives in conflict with one's own.
• Demonstrates a commitment to enhancing one's own awareness, knowledge, and skills related to equity, diversity, and inclusion.
• Undergraduate degree in a relevant discipline, or graduation from a technical college or institute is required.
• A MSc in a relevant discipline is preferred.
• Prior expertise of sample preparation for structural biology including membrane proteins is preferred, as is knowledge of the general work flow of single particle cryoEM.

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